All news from Anaesthesiology

Modular Gene Enhancer Plays Role in Leukaemia

In a study published in Nature, scientists have found that the role of Myc (generation of new blood cells in bone marrow and role in cancer) is determined by a distant section of DNA that contains a cluster of gene enhancers. In certain blood cancer cells, this cluster has been altered, which affects Myc activity and thereby accelerates cancer growth and affects how cancer responds to chemotherapy. This cluster of enhancers might, therefore, be a suitable target for the treatment of blood cancer.

FDG-PET/CT Predicts Response to Immune Checkpoint Inhibitor Therapy

Researchers demonstrated the combined positron emission tomography / computed tomography ( PET / CT ) scanning early in treatment could identify whether the therapy will benefit a particular patient. As the therapy has potentially serious side effects, early determination of ineffectiveness could avert unnecessary risk exposure and provide the option of a different treatment.

Building on India’s family planning success

Social reformer Raghunath Dhondo Karve was well ahead of his time when he pioneered family planning in Mumbai in the 1920s. Independent India’s first government caught up in 1952 when it started the world’s first family planning programme. The recently released report on the fourth round of the National Family Health Survey (NFHS-4), carried out in 2015-16, shows where it has succeeded—and where shortcomings remain.

Patients In A Pre-Anaesthetic Clinic Should Be Taken Care In Hospital

According to this study, researchers declared in a pre-anaesthetic clinic (PAC), as in any clinical service, patient satisfaction is important. This may be influenced by many factors. The main factor adversely affecting patient satisfaction is time spent in the clinic. Total time spent in PAC can be split into two parts: waiting time and consultation time, which have been defined. Patients needing emergency surgery are also not seen as they are assessed in the operating theatre itself.

First Map Of Gene Regulation In Human Brain Evolution

In this study, researchers have developed the first map of gene regulation in human neurogenesis, the process by which neural stem cells turn into brain cells and the cerebral cortex expands in size. The scientists identified factors that govern the growth of our brains. Brain development is guided by the expression of genes in certain brain regions or cell types, as well as during specific time frames.

Private ERs Are Dominant In Communities With A Public Hospital

A study lead by Laura N. Medford-Davis, MD, MS, an assistant professor of emergency medicine at Baylor College of Medicine, and a healthcare consultant. Uninsured patients are the most affected. The practice of indirect referrals by non-public emergency departments and their affiliated physicians are prevalent in communities with a public hospital option. This study published in the issue of Academic Emergency Medicine (AEM), a journal of the Society for Academic Emergency Medicine (SAEM).

Association Of Antimicrobial Resistance Gene Detection With The ISS

In this study, researchers declared that antimicrobial resistance (AMR) is a global health issue. To minimize this threat to astronauts, who may be immunocompromised and thus at a greater risk of infection from antimicrobial resistant pathogens, a comprehensive study of the ISS “resistome’ was conducted. Using whole genome sequencing (WGS) and disc diffusion antibiotic resistance assays, 9 biosafety level 2 organisms isolated from the ISS were assessed for their antibiotic resistance.