In a milestone achievement for better understanding the development and function of the human placenta, scientists have derived and grown trophoblast stem cells for the first time.
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A new study published in the Journal of Child Psychology and Psychiatry found that children with attention deficit hyperactivity disorder (ADHD) engaged in substance use at a younger age than those without ADHD and had a significantly higher prevalence of regular marijuana and cigarette use into adulthood.
On average, former elite athletes survive longer than their brothers. In addition, their self-rated health and health-related habits are better in comparison to their brothers at an older age. This was clarified by Master of Health Sciences (Sports and Exercise Medicine) Titta Kontro from the Faculty of Sport and Health Sciences at the University of Jyväskylä. The study included in total 900 former elite athletes and their brothers.
In a new study, the researhcers have found that BMAA, a toxin linked to several neurodegenerative diseases, is present in high concentrations during cyanobacteria blooms in Lake Winnipeg.
Scientists used single-cell transcriptome analysis to identify a hitherto unknown precursor for a poorly understood subgroup of killer T cells that are primarily found in humans with chronic viral infections. The detailed analysis of the entirety of transcribed genes in more than 9,000 individual cells also revealed an unprecedented level of heterogeneity. The study findings published in the Science Immunology.
Greenwood Genetic Center (GGC) in collaboration with scientists from Canada have identified unique epigenetic signatures for nine neurodevelopmental disorders lending to a better method of diagnosis for disorders with much clinical overlap. The epigenetic signatures were developed through methylation analysis and were reported in The American Journal of Human Genetics .
Most people with lung disease carry mutations in one of the genes that build the proteins that form molecular motors inside cilia. A single misshapen piece of protein can make the whole machine grind to a halt. But a few people have errors in proteins that are not part of the motor. Researchers at Washington University School of Medicine in St. Louis report they have solved that puzzle: The nonmotor proteins are like factory workers who put the motor together. Mutations cause these proteins to assemble the motor incorrectly.
A study was conducted by researchers from Genomic Instability and Cancer Laboratory at Institute for Research in Biomedicine. They identified a key role for EXD2 in protein production in the mitochondria, the cellular organelles responsible for most of energy generation. The study is Published in Nature Cell Biology.
According to a retrospective case series, Some older patients with apparently idiopathic uveitis may in fact have sarcoidosis-associated disease, which can have cardiac consequences. The study findings were published in the JAMA Ophthalmology
According to results from an open-label randomized trial, extended-pulsed fidaxomicin, delivering 20 doses over a longer time period after initial daily dosing, appears superior to standard-dose vancomycin for sustained cure of Clostridium difficile infection in patients age 60 or older.The study results was published in the Lancet Infectious Diseases.
According to a new study, direct care experiences with transgender patients not only increases the confidence of medical providers in providing care, but more importantly provides the patient with a better experience.
A new study, published in the Journal of Clinical Oncology, suggests that regular exercise could extend the life expectancy of breast cancer survivors, by lowering their increased risk of type 2 diabetes, heart disease, and potentially breast cancer recurrence.