According to a new study, researchers have discovered an entirely new class of ion channels. These channels let protons (H+ ions) into cells, are important in the inner ear for balance, and are present in the taste cells that respond to sour flavors. The study published in Science.
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A team of researchers from the University of Colorado Boulder have made important discoveries about a protein called AKT that is key to the formation of new memories.
Researchers to investigate the safety , cost-effectiveness, and clinical outcomes of bilateral total knee arthroplasty ( TKA ) in hemophilic arthropathy ( HA ), the requirements for transfusions, complications, costs, hospital stays, Hospital for Special Surgery (HSS) knee scores, knee range of motion ( ROM ) and revision rates were compared between bilateral bilateral and unilateral TKA in HA patients.
While palliative radiation therapy is used to ease the pain in patients with advanced lung cancer, it often has adverse effects like heartburn and difficulty swallowing. Through the PROACTIVE clinical trial, Lawson Health Research Institute scientist Dr. Alexander Louie is testing new palliative radiation techniques to spare these effects on the esophagus and improve quality of life for lung cancer patients.
A new study published in JAMA Oncology reports that for women who have survived Hodgkin's lymphoma, the risk for subsequent estrogen-receptor (ER)–negative breast cancer is nearly six times greater than for the general population. The study also found that the increased risk for ER-positive breast cancer is not as significant and is primarily associated with the previous radiotherapy.
Injecting breast cancer with oxygen-filled microbubbles makes tumors three-times more sensitive to radiation therapy and improves survival in animal models of the disease. The study in the International Journal of Radiation Oncology* Biology* Physics (IJROBP) makes a strong case for moving this technology into clinical trials with breast cancer patients.
A multifaceted pharmacist intervention can reduce the number of hospital readmissions and emergency department visits, according to a new study published in the Journal of JAMA Internal Medicine. A statistically significant reduced rate of readmissions after inclusion was observed in patients randomized to receive an extended pharmacist intervention compared with those who received usual care or a basic pharmacist intervention.
The U.S researchers have gained new insights into how the small intestine repairs itself after the injury caused by intestinal rotavirus infection. Their findings have led them to propose that how the intestine repairs itself seems to depend on the type of damage, and they found that triggers are actually essential for repairing the virus-caused injury. The study appeared in Cell Reports.
A University of Colorado Cancer Center study lays the scientific groundwork for the use of PD-1 inhibitors with an aggressive form of brain cancer , namely s upratentorial pediatric ependymoma . The study findings were published in the journal Pediatric Blood Cancers
In a study, researchers examined observational study of Children with Klippel-Feil syndrome (KFS), characterized principally by abnormal fusion of 2 or more cervical vertebrae, may have many additional congenital anomalies. The overall prevalence of otolaryngologic manifestations among patients with KFS has not been previously characterized.
Antipsychotic drugs cause severe side effects in individuals with schizophrenia, bipolar disorder, and autism-spectrum disorders. Now, scientists at the UNC School of Medicine and UC San Francisco (UCSF) have solved the first high-resolution crystal structure of the dopamine 2 receptor (DRD2) bound to the antipsychotic drug risperidone, yielding a long-awaited tool for drug developers, psychiatrists, and neuroscientists.