All news from Anaesthesiology

Safety and Clinical Outcomes of Simultaneous Bilateral TKA in HA

Researchers to investigate the safety , cost-effectiveness, and clinical outcomes of bilateral total knee arthroplasty ( TKA ) in hemophilic arthropathy ( HA ), the requirements for transfusions, complications, costs, hospital stays, Hospital for Special Surgery (HSS) knee scores, knee range of motion ( ROM ) and revision rates were compared between bilateral bilateral and unilateral TKA in HA patients.

Lymphoma Linked to Risk for Breast Cancer

A new study published in JAMA Oncology reports that for women who have survived Hodgkin's lymphoma, the risk for subsequent estrogen-receptor (ER)–negative breast cancer is nearly six times greater than for the general population. The study also found that the increased risk for ER-positive breast cancer is not as significant and is primarily associated with the previous radiotherapy.

Bursting Microbubbles Improve Breast Cancer Radiation Therapy

Injecting breast cancer with oxygen-filled microbubbles makes tumors three-times more sensitive to radiation therapy and improves survival in animal models of the disease. The study in the International Journal of Radiation Oncology* Biology* Physics (IJROBP) makes a strong case for moving this technology into clinical trials with breast cancer patients.

Multifaceted Pharmacist Intervention Prevent Hospital Readmissions

A multifaceted pharmacist intervention can reduce the number of hospital readmissions and emergency department visits, according to a new study published in the Journal of JAMA Internal Medicine. A statistically significant reduced rate of readmissions after inclusion was observed in patients randomized to receive an extended pharmacist intervention compared with those who received usual care or a basic pharmacist intervention.

Study Sheds light on How the Intestine Repairs Itself

The U.S researchers have gained new insights into how the small intestine repairs itself after the injury caused by intestinal rotavirus infection. Their findings have led them to propose that how the intestine repairs itself seems to depend on the type of damage, and they found that triggers are actually essential for repairing the virus-caused injury. The study appeared in Cell Reports.

A Breakthrough that could Lead to Better Antipsychotic Therapy

Antipsychotic drugs cause severe side effects in individuals with schizophrenia, bipolar disorder, and autism-spectrum disorders. Now, scientists at the UNC School of Medicine and UC San Francisco (UCSF) have solved the first high-resolution crystal structure of the dopamine 2 receptor (DRD2) bound to the antipsychotic drug risperidone, yielding a long-awaited tool for drug developers, psychiatrists, and neuroscientists.