All news from Anaesthesiology

Zika Virus: Repurposed Drug found to be Effective

In both cell cultures and mouse models, a drug used to treat Hepatitis C effectively protected and rescued neural cells infected by the Zika virus — and blocked transmission of the virus to mouse fetuses. Researchers say their findings support further investigation of using the repurposed drug as a potential treatment for Zika-infected adults, including pregnant women.

Targeted Probes for Lung Inflammation Detection with PET

Researchers aimed to develop a potent MMP probe , specifically targeting MMP-12 and MMP-9, based on ML5 for noninvasive COPD imaging with PET . As attachment of the  18 F-fluorobenzoyl moiety Decreased the affinity of ML5 Toward MMP-12, we selected another prosthetic agent for radiofluorination, 4-nitrophenyl 2- Namely 18 F-fluoropropionate ( 18 F-NFP ) .

An Unexpectes Rise in Rates of Diabetes, Hypertension found in India

Rates of diabetes and hypertension are high among middle-aged and elderly people across all geographic measures and sociodemographic groups in India, according to the first nationally representative study of those conditions in the country. The study, led by researchers at Harvard T.H. Chan School of Public Health, also found unexpectedly high rates of hypertension among young adults. The study appears online in JAMA Internal Medicine.

MMV Malaria Box Phenotyped against Pathogenic Parasites

A Singapore-India collaborative research project between the Singapore University of Technology & Design (SUTD) and CSIR-National Chemical Laboratories (NCL) completed phenotypic screening of a large collection of potent chemical inhibitors (known as MMV Malaria Box), against pathogenic parasites Toxoplasma gondii and Plasmodium falciparum, causative agents of human toxoplasmosis and malaria.