All news from Anaesthesiology

Study Finds, Drug Safety in Hospitalized Pediatric Patients

The results of the study, recently published in BMC Pharmacology and Toxicology, identified 19 ADRs out of a total of 1,083 hospital admissions.The most frequently prescribed drug classes were antibiotics and anti-inflammatory drugs. The approximate incidence of ADRs in children was17per 1,000 children.Most of the ADRs involved antibiotics and 21% of the ADR’s were categorized as “preventable”. The severest ADRs observed during the study were haemolysis and toxic epidermal necrolysis.

In Comparison Of Transfemoral with Non-TF For TAVR; Study Tested

In this study, researchers showed comparison study of Transfemoral (TF) access is associated with lower rates of surgical conversion and mortality compared with non-TF access for Transcatheter aortic valve replacement (TAVR). Therefore, efforts should be made to make this procedure even less invasive, allowing more TAVR procedures to be performed through femoral access. We herein describe our single-center experience of using one-stage percutaneous internal endoconduits for TAVR in patients with unfavorable iliac artery anatomy.

Association between Higher PLR Levels and Risk of Sarcopenia in Older People

A new study published in the Scientific Reports has reported that higher platelet-to-lymphocyte ratio (PLR) levels are associated with a greater risk of sarcopenia in geriatric populations. Thus, PLR as an inexpensive and easily measurable parameter can be considered as an inflammatory biomarker for sarcopenia. Researchers found that PLR levels were greater in patients with sarcopenia than in those without sarcopenia.

Duchenne Muscular Dystrophy Analysis

Researchers are searching for therapies that might slow the progression of DMD while also investigating genetic and other approaches to disrupt the underlying disease mechanism. Examining data from the large TREAT-NMD Duchenne muscular dystrophy database, investigators were able to confirm that corticosteroid treatment can delay some of the clinical effects of DMD and that there is greater variability among patients in the progression of the disease than reported. These findings appear in the Journal of Neuromuscular Diseases .