All news from Anaesthesiology

New Drug Target that may Reduce GVHD Risk, researchers find

Stem cell transplants can cure patients with high-risk leukemia or lymphoma. Graft-versus-host disease (GVHD) is a potentially life-threatening side effect that occurs when the donor's immune cells attack the recipient's normal tissues. Moffitt Cancer Center researchers are trying to identify new drug targets to reduce the risk of GVHD. Their new study, published in the Proceedings of the National Academy of Sciences, shows a drug that targets the protein JAK2 may reduce the risk of GVHD.

Properties of Physiological Tests in Rugby measured

The systematic review was conducted with the first objective aimed at providing an overview of the physiological characteristics commonly evaluated in rugby and the corresponding tests used to measure each construct. Secondly, the measurement properties of all identified tests per physiological construct were evaluated with the ultimate purpose of identifying tests with the strongest level of evidence per construct.

CKD: Body Composition is Associated with Erythropoiesis

In the general population, adiposity influences erythropoiesis and iron metabolism. Researchers aimed at assessing the relationship between adiposity [estimated by body mass index ( BMI ) and abdominal circumference ( AC )] and biomarkers of erythropoiesis in patients with chronic kidney disease ( CKD ) not on dialysis .

A deadly measles outbreak that killed children in Indonesia

In this study, researchers evaluated in terms of outbreaks in Indonesia. A deadly measles-and-malnutrition outbreak that killed scores of children in Indonesia's remote Papua province is over. According to statistics showed a total of 72 children died while hundreds more were sickened because of the "extraordinary" outbreak, which hit several isolated communities in Papua's Asmat district between September 2017 and February 4.

Genetic Cause behind Rare High Blood Pressure Syndrome Discovered

Twenty-five years ago, an unusual inherited form of high blood pressure was first described in an Australian family. Its genetic cause, however, had remained elusive. Using modern sequencing methods, an international research team led by BIH Johanna Quandt Professor Ute Scholl has succeeded in detecting mutations in a new disease gene (CLCN2), present in this family and seven others that are responsible for the development of a familial form of hyperaldosteronism .

Opinions of General Practitioners about Psychotherapy

A new study published in the PLoS One has reported that general practitioners (GPs) had distinct attitudes toward psychotherapy, falling into three different categories according to their opinions of this type of treatment. The majority of general practitioners (GPs) were reasonably favourable to psychotherapy.

Yeast Membrane Revealed by Extreme Microscopy

Researchers observed that these proteins move extremely slowly in the plasma membrane of the yeast and discovered how they travel through the membrane to reach the islands. They made these observations with state-of-the-art super-resolution optical microscopy. These membrane compartments appear to store transport proteins. The study is published in Natural communications