Researchers at Johns Hopkins, the University of California, Davis, and the National Institute of Allergy and Infectious Diseases have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus (staph). The findings, published in The Journal of Clinical Investigation, open new doors to someday developing vaccines to prevent staph skin infections.
All news from Anaesthesiology
According to a study published in the PLoS One, the physicians, nurse practitioners, and physician assistants responding to the survey agreed that practice variation should be reduced, but many seemed to have reservations about the feasibility of this aim. Time to appraise and apply practice standards was rated as most helpful in standardizing practice.
A new study, published in Mucosal Immunology, suggested that intestinal microbiome plays a substantial role in the development of obesity and insulin resistance in mammals, including humans. The findings highlight the potential to prevent obesity and diabetes by manipulating levels and ratios of gut bacteria, and/or modifying the chemical and biological pathways for metabolism-activating genes.
In a new study, researchers identified a new technique to compare biomechanically, a novel technique designed to repair PMMR tears using tendon graft (TG) and conventional TPS repair. Transtibial pullout suture (TPS) repair of posterior medial meniscus root (PMMR) tears was shown to achieve good clinical outcomes. The tendon grafts and sutures were threaded through the bone tunnel and then fixed to the anterolateral cortex of the tibia.
Mature human hepatocytes are critical in preclinical research and therapy for liver disease but are difficult to manipulate and expand in vitro. Hepatic stem cells (HpSCs) may be an alternative source of functional hepatocytes for cell therapy and disease modeling.
In a study published in the Annals of Rheumatic Diseases, the research team led by Denis Evseenko from Keck School of Medicine of USC, describes the promise of a new molecule aptly named "Regulator of Cartilage Growth and Differentiation," or RCGD 423 for short.
In a new research published in Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, scientists have designed an antibody-based therapy that prevents collagen molecules from aggregating together and forming fibrils, the building blocks of fibrotic tissue and thus to treat organ fibrosis.
According to this new study, researchers have recognized an enzyme, a special pair of RNA scissors, which is involved in CRISPR/Cas systems and the correct regulation of gene expression. The study has published their work in the scientific journal Nature Microbiology.
According to this study, researchers have restored the levels of coenzyme Q10 (CoQ), a key molecule in energy production in cells, could overcome insulin resistance or pre-diabetes, a precursor to type 2 diabetes and cardiovascular disease. Levels of CoQ and the presence of insulin resistance were analysed in a range of experimental laboratory settings, mouse models and samples from humans. The study is Published in eLife.
To better understand the antibiotic resistant organisms spread, researchers at the National Institutes of Health (NIH), recently collected samples from pipes under the hospital's intensive care unit and from outside manholes draining hospital wastewater. They conducted whole-genome analyzes on the samples to study the bacterial plasmids, or rings of DNA, that can confer resistance to antibiotics.
New research published today in The Lancet Infectious Diseases, suggests the effectiveness of the large-scale distribution of medication (known as Mass Drug Administration or MDA) to treat lymphatic filariasis (LF) in urban areas needs to be re-examined.
The aim of this study is to evaluate the use of 18F-Fluorocholine-PET / CT for preoperative localization in patients with Primary Hyperparathyroidism ( pHPT ) and negative / equivocal 99m Tc-sestamibi scintigraphy / SPECT / CT and / or ultrasound.