Research Finds The Mechanisms Behind Cognitive Decline in Type 2 Diabetes
Type 2 diabetes has been linked with an increased risk of cognitive dysfunction and dementia, but the underlying mechanisms are uncertain, according to the study
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CRISPR Screen Identifies Gene Against Flavivirus Infection
Researchers now report the first use of CRISPR genome-wide screening to identify a gene that helps cells resist flavivirus infection. UT Southwestern researchers today report the first use of CRISPR genome-wide screening to identify a gene that helps cells resist flavivirus infection. That nasty class of pathogens includes West Nile virus, dengue fever, Zika virus, and yellow fever.
Hypertrophic Cardiomyopathy Related to Sudden Death, Findings
About one person out of 500 has a heart condition known as hypertrophic cardiomyopathy (HCM). This condition causes thickening of the heart muscle and results in defects in the heart's electrical system. Under conditions of environmental stress such as exercise, HCM can result in sudden death. In other cases, patients may go undiagnosed, with their heart function declining gradually over decades. The study, published in Nature Biomedical Engineering
New Method To Predict Prostate Cancer Risk
The grade group (GG) is superior to the Gleason score (GS) for distinguishing between prostate cancer risk groups, according to new findings. Both GG and GS are derived from needle-core biopsies in patients with suspected prostate cancer or analysis of a radical prostatectomy specimen.
More Doctor Visits Lead to Fewer Suicide Attempts for Fibromyalgia Patients
Fibromyalgia patients who regularly visit their physicians are much less likely to attempt suicide than those who do not, according to a new Vanderbilt University Medical Center study published in Arthritis Care & Research
PPI Use in Infants Not Linked with Increased Risk of Lung Infections, Findings
New University of Otago research shows infants using popular anti-reflux medicines like omeprazole are not at increased risk of pneumonia or other lower respiratory tract infections, contrary to findings from other international studies.
Promising Approach Against Acne, Laboratory Studies
Topical retinoids, which target retinoic acid receptors, are commonly used to treat acne. New research published in the British Journal of Dermatology reveals that trifarotene, a fourth-generation retinoid with potent and selective activity against only one particular retinoic acid receptor, may have an improved efficacy and safety profile compared with less selective retinoids. To characterize the in vitro metabolism and the pharmacology of the novel retinoid trifarotene.
Fish-Rich Diets Boost Babies' Brain Development
Women could enhance the development of their unborn child's eyesight and brain function by regularly eating fatty fish during pregnancy. This is the suggestion from a small-scale study led by Kirsi Laitinen of the University of Turku and Turku University Hospital in Finland, in the Springer Nature-branded journal Pediatric Research.
Exercise May Delay Cognitive Decline in People with Rare Alzheimer's Disease
For individuals carrying a genetic mutation that causes Alzheimer's disease, engaging in at least 2.5 hours of physical activity per week may have beneficial effects on markers of Alzheimer's disease brain changes and may delay cognitive decline, according to a new study available online by Alzheimer's & Dementia: The Journal of the Alzheimer's Association as an article in press, corrected proof
Study Findings: One in Three Opioid Prescriptions in the US not Justified
According to a nationwide analysis of physician visit records conducted by a team of researchers at Harvard Medical School and the RAND Corporation, nearly 30% of the outpatient opioid prescriptions made out in the United States do not have documented the justification for their use.
Oral Steroids For The Resolution of Otitis Media With Effusion In Children
A new study by researchers at Cardiff University and the University of Oxford shows that a one-week course of oral steroid tablets does not result in large benefits for most two- to eight-year-old children who have had glue ear with hearing loss for at least three months.
CT Imaging Aids Physicians Discuss Risks, Tx With Parents
A series of illustrations and charts designed as decision aids for parents of children with minor head injuries helped them communicate with emergency medicine physicians and make informed decisions about their child's care.