All news from Anaesthesiology

Calcium In Brain Cells May Lead To Development Of Parkinson's Disease

Researchers have found that excess levels of calcium in brain cells may lead to the formation of toxic clusters that are the hallmark of Parkinson's disease. They identified that calcium can mediate the interaction between small membranous structures inside nerve endings, which are important for neuronal signalling in the brain, and alpha-synuclein, the protein associated with Parkinson's disease. The study is published in the journal Nature Communications.

Prostrate Cancer: FDA-approved New Treatment

The U.S. Food and Drug Administration approved Erleada (apalutamide) for the treatment of patients with prostate cancer that has not spread (non-metastatic), but that continues to grow despite treatment with hormone therapy (castration-resistant). This is the first FDA-approved treatment for non-metastatic, castration-resistant prostate cancer.

Psoriasis Treating Drug also Reduces Aortic Inflammation

A study presented at the

in San Diego has found that an antibody used to treat the skin disease psoriasis is also effective at reducing aortic inflammation, a key marker of future risk of major cardiovascular events. Researchers have found patients who took the drug ustekinumab had a 19% improvement in aortic inflammation, as measured and confirmed by imaging, when compared to the placebo group.

Health Burden of COPD in Nepal

Understanding the national prevalence, morbidity, and mortality associated with major NCDs with higher public health and socioeconomic impact, like COPD, is essential for evidence-informed policy planning and program implementation. The study aims to present the health burden of COPD in Nepal using the GBD 2016 dataset.