Conventional type 1 dendritic cells (cDC1) are critical for antitumor immunity, and their abundance within tumors is associated with immune-mediated rejection and the success of immunotherapy. Here, we show that cDC1 accumulation in mouse tumors often depends on natural killer (NK) cells that produce the cDC1 chemoattractants CCL5 and XCL1.
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According to a research review, Babies who are born much too soon or who arrive weighing too little may not score as high on intelligence tests during childhood as full-term infants.
Midwife-friendly laws and regulations tend to coincide with lower rates of premature births, cesarean deliveries and newborn deaths, according to a U.S.-wide "report card" that ranks each of the 50 states on the quality of their maternity care. The study was published online on Feb. 21 in PLOS ONE.
According to this study, researchers examined a small set of nerve cells in the brain prevents convulsive seizures in a mouse model of temporal lobe epilepsy, the most common form of epilepsy among human adults. Researchers found Inactivating this nerve-cell population also induces the same cognitive losses that characterize chronic, drug-resistant temporal lobe epilepsy in humans. This study is be published in Science.
The present study represents the first time that positron emission tomography (PET) imaging has been used to determine mGluR5 binding in vivo in brains of adults with autism and controls, using [18F]-3-fluoro-5-[(pyridin-3-yl)ethynyl]benzonitrile ([18F]-FPEB), a potent, selective, and systemically active antagonist of mGluR5.
Researchers aimed to investigate if mGluR5 expression in vivo replicated the results obtained by postmortem experiments and whether these changes (if any) positively correlated with autism symptom severity.
A groundbreaking new wearable, stretchable electronics designed by Northwestern University engineering professor John A. Rogers, in partnership with Shirley Ryan AbilityLab, which can be worn on the throat could be a game-changer in the field of stroke rehabilitation.
According to this study, researchers analyzed the mechanism of injury for traumatic TMPs among patients presenting to the ED. In this cross-sectional analysis of 949 emergency department visits, foreign body instrumentation was the most frequent cause of traumatic tympanic membrane perforations. The leading cause of traumatic tympanic membrane perforations(TMPs) may be preventable, and patient education may prevent this frequent cause of injury.
According to a new study, researchers have shown that symptoms of heart attack may often be missed among women aged 55 years or less as these symptoms may be less common than the traditional chest pains. The study reveals that over half of the physicians who attend to these women may miss the symptoms to be caused by heart attacks before these women are eventually hospitalized. This study has published in Circulation.
New blood and urine tests which can indicate autism in children have been developed by researchers at the University of Warwick. The tests could lead to earlier detection of autism spectrum disorders (ASD) and consequently, children with autism could be given appropriate treatment much earlier in their lives.
A study elucidates that a journey to Mars will be a large milestone for all humankind. Throughout history, health dangers associated with exploratory voyages to expand our frontiers. Travelling through deep space, the final frontier, is planned for the 2030s by NASA. The lessons learned from the adverse health effects of space exposure have been encountered from previous, less-lengthy missions.
The enzyme that produces DNA building blocks plays an important role when cells divide. In a new study published in eLife, researchers have discovered for the first time that the so-called master switch of the enzyme can change locations — while still performing the same task.
With widespread flu activity across most of the U.S., avoiding exposure can be difficult, but Loyola Medicine primary care physician Mary Barsanti-Sekhar offers some advice to minimize the risk and protect children from the flu.