All news from Anaesthesiology

Study Uncovers Genetic Cause Behind Drug-resistant Typhoid Strain

The genetic cause behind a strain of typhoid's resistance to five classes of antibiotics has been uncovered by scientists at the Wellcome Sanger Institute and their collaborators at Public Health England and Aga Khan University, Pakistan. The results, published in mBio suggest that treatment options are running out for typhoid, and there is an urgent need for preventative strategies including vaccines.

To Create Nanoscale Materials By Using DNA Material

A team of researchers has produced 3-D images from 129 individual molecules of flexible DNA origami particles. Their work provides the first experimental verification of the theoretical model of DNA origami. Over the past decade, researchers have been working to create nanoscale materials and devices using DNA as construction materials through a process called "DNA origami." The study has published in Nature Communications.

Aspirin, Rivaroxaban Similar After Arthroplasty

Among patients who underwent total hip or total knee arthroplasty, aspirin did not differ significantly from rivaroxaban (Xarelto, Janssen Pharmaceutica) for prevention of proximal deep-vein thrombosis or pulmonary embolism, after both groups received a 5-day course of rivaroxaban immediately after surgery, a large trial found.

An Adult Brain Can Produce New Neurons

Scientists have established that the new neurons produced in adults react preferentially to reward-related sensory stimuli and help speed up the association between sensory information and reward. Adult-born neurons therefore play an important role in both the identification of a sensory stimulus and the positive value associated with that sensory experience. This stuyd has published in  Proceedings of the National Academy of Sciences (PNAS).

New Light on Immune Cell Identity

Almost all cells in the human body have identical DNA sequences, yet there are 200-plus cell types with different sizes, shapes, and chemical compositions. Determining what parts of the genome are read to make protein and which are silenced is orchestrated by proteins called transcription factors. These regulate the availability of distinct stretches of DNA to be expressed as opposed to others that remain buried in tightly coiled structures called chromatin.