All news from Anaesthesiology

Genome Sequencing and Epidemiologic Analysis Of Institutional Influenza Outbreaks

Adequacy of the current clinical definition of institutional influenza outbreaks is unclear. We performed a retrospective genome sequencing and epidemiologic analysis of institutional influenza outbreaks that occurred during the 2014–15 influenza season in Toronto, Canada. They sequenced the 2 earliest submitted samples positive for influenza A(H3N2) from each of 38 reported institutional outbreaks in long-term care facilities.

Risks of Transplants Minimized

A bone marrow transplant is often the only therapy available to save leukemia patients, but the risk of complications is high. In spite of devoting considerable time and effort to finding a suitable donor, nearly half of all patients experience an unwanted reaction of their immune system, which often attacks their skin and liver and in up to 50% of cases the intestines.

Researchers at FAU have succeeded in deciphering what causes this in some instances life-threatening inflammation of the intestines, possibly opening up new approaches for treatment. They have published the results of their research in the Journal of Clinical Investigation.

New Therapeutic Approach Stabilizes Nerve-Muscle Synapses in ALS Mouse Model

A new study led by NYU School of Medicine researchers identifies a novel treatment strategy that preserved neuromuscular synapses in a mouse model of aggressive amyotrophic lateral sclerosis. The study, published in the journal eLife, found that the loss of such synapses was reduced in ALS mice injected with antibodies that stimulate a molecule in the muscle which keeps nerves attached to the muscle.

Women Show Evidence Of Previous Heart Attack Scars

Women who complain about chest pain often are reassured by their doctors that there is no reason to worry because their angiograms show that the women don't have blockages in the major heart arteries, a primary cause of heart attacks in men. Researchers show that about 8% of those women actually have scars on their heart that indicate they experienced a heart attack. The study has published in Circulation.

Advanced MR Imaging may Help Avoid Unnecessary Biopsies

The scientists from the German Cancer Research Center (DKFZ), have combined an advanced method of diffusion-weighted MR imaging with intelligent image analysis methods to detect malignant changes in tissues. This method may prevent many control biopsies following suspicious findings from mammography screenings. This advancement holds promise for substantial improvements in the diagnosis of breast cancer.