All news from Anaesthesiology

Kids after Heart Surgery and Mortality Risks

Children from low-income neighborhoods had a higher mortality rate and higher hospital costs after heart surgery compared with those from higher-income neighborhoods, found a national study of more than 86,000 kids with congenital heart disease. The magnitude of the neighborhood effect, which persisted even after accounting for race, type of insurance, and hospital, was similar for children of all disease severities. The findings were published online today in Pediatrics.

Typbar-TCV: First African Child Immunized

The first African child was vaccinated with the newly prequalified World Health Organization (WHO) typhoid conjugate vaccine (TCV), Typbar-TCV, in Malawi. The clinical trial is led by Principal Investigator Professor Melita Gordon of the University of Liverpool and the Malawi-Liverpool-Wellcome Trust (MLW) Clinical Research Programme. A total of 24,000 children in Ndirande and Zingwangwa townships will be enrolled in the Malawi trial.

An Advanced Therapies For Crohn's Disease

In a recent study, researchers determined the use of advanced therapies for Crohn's disease (CD) has not significantly altered the natural disease course and phenotypes compared with those reported before the era of biologic therapies. This study is published in Gut.

An Achilles heel of Trypanosomes discovered

Trypanosomes are single-celled parasites that cause diseases such as human African sleeping sickness and Nagana in animals. But they are also used in basic research as a model system to study fundamental biological questions.

Researchers of the University of Bern have now investigated how trypanosomes equally distribute their "power plant" to the daughter cells during cell division. The discovered mechanism potentially opens new avenues for drug interventions.