Researchers have shown that probenecid, a drug long used to treat gout, may be able to improve heart function in adult patients who experience heart failure. The study has published in the Journal of the American Heart Association.
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Respiratory disease patients with arthritis could struggle to manage their conditions because their inhalers are too fiddly for them to use, according to University of Bath research published in Respiratory Medicine.
It's OK for doctors to start using a kid-friendly nasal spray flu vaccine again, a federal panel said. Two years ago, the advisory group pulled its recommendation for FluMist vaccine after research found it wasn't working against swine flu, the kind of flu that was making most people sick then. But the Advisory Committee of Immunization Practices voted 12-2 Wednesday to recommend the nasal spray as an option for next winter's flu season.
The WHO recommends using the Kato-Katz technique to detect detect intestinal schistosome infections. This technique analyzes slides of fecal matter. But the approach often misses people who are infected with only a low burden of parasites and, as a consequence, shed only a few eggs in fecal samples. Researchers have now analyzed the efficacy of other testing approaches in a setting with low parasite burden; their results appear in PLOS Neglected Tropical Diseases.
A study found the levels of a protein found in the brain called alpha-synuclein (α-syn) are significantly lower than normal in cerebrospinal fluid collected in Parkinson's disease patients suffering from postural instability and gait difficulty. The study was published online in the journal Movement Disorders.
Systemic family therapy is not superior to treatment as usual in reducing subsequent acts of self-harm in adolescents who have a history of the disorder, a new study published in Lancet Psychiatry suggests.
A team of scientists from the University of Colorado School of Medicine and the Charles C. Gates Center for Regenerative Medicine at CU Anschutz has reported a more efficient approach to reprogramming a patient's diseased skin cells into stem cells, raising hopes for future clinical trials and potential cures for critical illnesses. The results were published in the journal Nature Communications.
Scientists don't agree on when and how this dramatic increase took place, but new analysis of 94 hominin fossils shows that average brain size increased gradually and consistently over the past three million years. Modern humans have brains that are more than three times larger than our closest living relatives, chimpanzees and bonobos. This study has published in the Proceedings of the Royal Society.
Researchers found that giving mice particular microbes increased blood levels of immunoglobulin A (IgA) antibodies, which protected against the kind of widespread bacterial invasion that leads to sepsis. The fight against sepsis could get a helping hand from a surprising source: gut bacteria. The study has published in the journal Cell Host & Microbe.
The steady march of technological progress has finally shone its light into the dingy world of the mugshot – the commonplace name given to the photograph of a police suspect. The mugshot represents one of the earliest uses of technology in the identification of criminals. It has proved to be a particularly useful way of identifying recidivists – people who repeatedly reoffend.
UC San Diego Health now offers patients with epilepsy, a non-pharmacological way to treat seizures . For the more than one million individuals who live with uncontrolled seizures despite taking medications, UC San Diego Health recently began offering the first and only FDA-approved brain-responsive neurostimulation (RNS) system designed for the treatment of refractory epilepsy.
A recent Journal of Bone and Mineral Research analysis indicates that screening for fracture risk in older postmenopausal women is a good use of healthcare resources—in other words, it's cost-effective. The current study aims to use resource-use and outcome data collected as part of the SCOOP study to estimate the cost-effectiveness of the SCOOP screening intervention over a 5-year time horizon.