In this study, researchers have succeeded in stopping the growth of malignant melanoma by reactivating a protective mechanism that prevents tumor cells from dividing. The team used chemical agents to block the enzymes responsible for erasing epigenetic marks at the DNA. This discovery has potential for use in future combination therapies. The study is published in the journal Cancer Cell.
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In this study, researchers estimated that the extraordinary for people in their 80s and 90s to keep the same sharp memory as someone several decades younger, and now scientists are peeking into the brains of these "superagers" to uncover their secret. The work is the flip side of the disappointing hunt for new drugs to fight or prevent Alzheimer's disease.
An interdisciplinary team from the Technical University of Munich (TUM) developed a new staining method for histological examination of three-dimensional tissue samples using nano-scale computed tomography, according to a study published in the current issue of PNAS.
In this anatomical study, the lateral arm flap is used for composite defects in need of vascularized soft tissue, skin, and bone. From its original description, the distal humeral metaphysis can be included with the flap, supplied by the periosteal extensions of the posterior branch of the radial collateral artery. Researchers wanted to reexplore the anatomy of the lateral arm to determine its utility as a donor site for vascularized bone.
Researchers demonstrated a novel process to produce cell-sized lipid vesicles (CLVs) from microfluidically generated double emulsion templates by investigating the interfacial parameters that control double emulsion stability for storage, and their subsequent dewetting to form multisomes or GUVs (subsets of CLVs). A report detailing this latest development was published in the journal TECHNOLOGY.
In this study, researchers examined while type 2 diabetes (T2D) was once considered a disease largely confined to older people, the global epidemic of obesity and overweight has seen diagnoses rocket in young adults, adolescents and even appear in young children. The study is published in Diabetologia.
Thousands of British women could soon benefit from a new breast cancer ‘blaster’ (Intra-operative Radio Therapy) that spares them the ordeal of daily radiotherapy after surgery.
The procedure for patients with small, early-stage tumors replaces up to six weeks of treatment with a single 30-minute session that has been proved to be as effective in preventing the disease from returning.
According to a post hoc analysis of the EXCEL study, atrial fibrillation (AF) develops in almost one in five patients after left main coronary artery bypass surgery and is one of the strongest predictors for subsequent stroke and death.
New CHILD Study research has found that overweight and obese women are more like to have children who are overweight or obese by three years of age–and that bacteria in the gut may be partially to blame.
A new study published in the journal Annals of Internal Medicine, which was performed at the Leeds Institute of Rheumatic and Musculoskeletal Medicine in the United Kingdom, found that hydroxychloroquine is no more effective than placebo in reducing symptoms or radiographic progression in patients with moderate to severe hand pain and radiographic osteoarthritis (OA).
According to a study, researchers examined that the antibiotic clarithromycin may increase the long-term risk of heart problems and death in patients with heart disease. The federal Food and Drug Administration said Thursday that it's recommending that doctors carefully weigh the benefits and risks of the drug before prescribing it to patients with heart problems.