All news from Anaesthesiology

A Protein That Moves from A Cell's Mitochondria To Its Nucleus

In this study, researchers have identified a protein, G-Protein Pathway Suppressor 2 (GPS2), that moves from a cell's mitochondria to its nucleus in response to stress and during the differentiation of fat cells. The researchers conducted their study in cell cultures and experimental models that had been genetically modified to lose the expression of GPS2. The study has published online in the journal Molecular Cell.

Insights Of Dry, Inflamed And Itchy Skin That Plagues Eczema Patients

Researchers have revealed a cause of the dry, inflamed and itchy skin that plagues eczema patients. Medical researchers have now shown that an immune system skewed toward allergy alters the lipids in the skin. The altered lipids allow the skin to crack, water to leave and irritants to enter, setting the stage for eczematous lesions to develop. The study has published in the journal JCI Insight.

A New Approach to Treat Microbial Keratitis

Microbial infections of the cornea can have serious consequences, including blindness in the worst case. The treatment of keratitis, a condition caused by certain pathogens, always presents major challenges to ophthalmologists. These corneal infections frequently cannot be successfully treated with the therapies currently available. Fraunhofer researchers are pursuing a new approach: contact lenses with germicidal properties could offer an alternative to conventional therapies. Initial tests in the laboratory and on donor corneas were successful.

Vitamins Can Be Encapsulated And Stored For Extended Spaceflight

In this study, alkaline-degradable microgels based on poly(N-vinylcaprolactam) (PVCL) were prepared and analysed with their regard to stabilise retinol which acts as a model vitamin (vitamin A1). Biocompatible materials that can encapsulate large amounts of nutrients while protecting them from degrading environmental influences are highly desired for extended manned spaceflight.

Eating Nuts Improved CRC Survival

A new study estimated that patients with stage III colon cancer who were treated with surgery and adjuvant chemotherapy. For those patients who recalled eating two servings of nuts per week, disease-free survival (DFS) and overall survival (OS) were significantly extended compared to those who had not consumed any nuts. Association was significant only for eating tree nuts, which include almonds, walnuts, hazelnuts, cashews, and pecans.