All news from Anaesthesiology

Lymphoma: Epigenetics Therapy Shows promising Cure

New compounds targeting epigenetics have shown remarkable early activity in patients with lymphoma, according to data presented at the TAT (Targeted Anticancer Therapies) International Congress 2018 in Paris, France. ESMO's phase-I oncology meeting featured early clinical studies with BET inhibitors and EZH2 inhibitors.

Development of a Cost-Effective Way to Culture Stem Cells

Human pluripotent stem cells (hPSCs) can infinitely self-renew and develop into all major cell types in the body, making them important for organ repair and replacement. But culturing them in large quantities can be expensive. Now researchers have developed a more cost-effective culture by using a new combination of chemical compounds.

Lung cancer: Clustering of Multi-Parametric Functional Imaging

The researchers aimed to derive a methodology to combine multiple functional imaging techniques to identify high-risk tumour subregions in NSCLC patients treated with (chemo)radiotherapy. Therefore, we developed a data-driven clustering approach to correlate the subregions to patient prognosis using FDG PET/CT to quantify metabolic activity, HX4 PET/CT to visualize hypoxia, and dynamic contract-enhanced CT (DCE-CT) to assess tumor vasculature.

Human Heart Cells Can Divide, Multiply And Develop

In this study, the human heart cells can divide and multiply, allowing the heart to grow and develop. The problem is that, right after birth, cardiomyocytes their ability to divide. The same is true for many other human cells, including those of the brain, spinal cord, and pancreas. The study has published in the journal Cell.

Vaginal Ring for HIV Prevention

Nearly 90% of participants in an open-label study of a vaginal ring infused with a drug to prevent HIV are using the monthly ring at least some of the time, according to an interim analysis of study data. In addition, the rate of HIV infection among participants in the open-label study, which has no placebo arm for comparison, is half of what might be expected in the absence of the ring, according to mathematical modeling.

Role of Virus-blocking Bacterium in Mosquitoes

New research reveals details of the mechanism by which the bacterium Wolbachia blocks viruses in mosquito cells, suggesting that it reduces viral replication inside cells and that rapid degradation of viral RNA is involved. Professor Scott O'Neill, Program Director of the World Mosquito Program, led by Australia's Monash University, and colleagues report their findings in PLOS Pathogens.