All news from Anaesthesiology

Recurrent Cortical Circuits Implement Concentration-Invariant Odor Coding

If you can tell the difference between a merlot and a cabernet franc just by smell, it's probably all in the timing. That's because the odor-decoding centers of the brain will pay more attention to the first smell signals to reach them, regardless of how long or strong the remainder of the sniff may be, they have teased apart the neural circuitry of smell in mice. The study was published in Science.

Brigatinib Becomes Potential New First-line Option for ALK-positive Non-small Lung Cancer

Results of a 275-patient, multi-national phase III clinical trial known as ALTA-1L published today in the New England Journal of Medicine and presented concurrently in the press program at the International Association for the Study of Lung Cancer (IASLC) World Conference on Lung Cancer 2018 argue for brigatinib as a first-line treatment option for advanced ALK-positive non-small cell lung cancer

Proposals to Implement Smoke-Free Index, Foundations Issues

The Foundation for a Smoke-Free World announced at the Global Tobacco and Nicotine Forum that it is calling for proposals to develop and implement the Smoke-Free Index. The index will critically evaluate industry progress toward achieving a smoke-free world and assess actions taken to undermine that progress.

Tumor Cell Expansion Challenges Current Physics

A malignant tumor is characterized by its ability to spread around its surroundings. To do so, tumor cells stick to the surrounding tissue (mainly collagen) and use forces to propel. The study was published in the journal Nature Physics. They reveal the forces these tumor cells use to spread. The relation between these forces and the cell movement goes beyond current physical laws.

A Hydrogel Injection to Regenerate Cartilage, 3-D bioPen

Highly specialized cartilage is characteristically avascular and non-neural in composition with low cell numbers in an aliphatic environment. Despite its apparent simplicity, bioengineering regenerative hyaline cartilage in a form effective for implantation remains challenging in musculoskeletal tissue engineering.