All news from Anaesthesiology

Evaluate The Endoscopic Surgical Repair Of Ossicular

Researchers determine to evaluate our experience with endoscopic repair of ossicular discontinuity at the incudostapedial joint, with or without an intact stapes suprastructure and present our hearing results. They classify results based on the causative pathology, the type of ossiculoplasty, and kind of lesion.

They demonstrate the ability to endoscopically place a total ossicular replacement prosthesis (TORP), measuring 4.25 mm, between the stapes footplate and the incus remnant to re-establish ossicular continuity.

HPV: Communication Intervention Increases Vaccination in Teens

Rates of vaccination against the human papillomavirus (HPV) remain low among adolescents in the United States, despite the wide availability of the vaccine since 2006 for girls and 2009 for boys.

A new randomized controlled clinical trial suggests that patients may complete the HPV vaccine series when clinicians use an intervention specifically designed to facilitate communication with patients and their parents about the vaccine.

Effects of Aging on Pulmonary Vessels

A new study, published in the American Journal of Physiology—Lung Cellular and Molecular Physiology (AJP-Lung), suggests that certain areas of the lungs are more likely than other organs to show age-related damage that compromises respiratory function.

Canagliflozin Lowered The Risk In Patients With Type 2 Diabetes

Researchers examined that the antidiabetic sodium glucose co-transporter 2 (SGLT2) inhibitor canagliflozin lowered the risk for hospitalization for heart failure (HF) or dying of cardiovascular disease in patients with type 2 diabetes. In fact, in this exploratory analysis from the Canagliflozin Cardiovascular Assessment Study (CANVAS), the 14% of patients with type 2 diabetes who already had HF appeared to benefit most. "Importantly, that needs to be tested in a heart failure dedicated study."

Novel Approach for Anticancer Drug Delivery

With the goal of minimizing the side effects of chemotherapy on healthy tissues, a team of researchers at the Center for Self-assembly and Complexity, within the Institute for Basic Science (IBS) have developed novel nanocontainers able to deliver anticancer drugs at precise timing and location. Published in Angewandte Chemie International Edition, the study combines uniquely designed molecules and light-dependent drug release, which may provide a new platform to enhance the effect of anticancer therapeutics.

Researchers Identify Asthma Types with Common Biological Features

People with mild asthma can be identified from those with moderate or severe asthma using the identified biological variations in lung tissue samples, according to a research published in the Journal of Allergy and Clinical Immunology. The stud was led by the researchers from the NIHR Leicester Biomedical Research Centre – a partnership between Leicester’s Hospitals, the University of Leicester and Loughborough University.

New Approach to Alleviate the Chronic Pain

In a collaborative study, researchers at the Institute for Neurosciences of Montpellier (INSERM) and the Laboratory for Therapeutic Innovation (CNRS/Université de Strasbourg) have unravel the mechanism behind the appearance and continuation of neuropathic pain. The study findings, published in the Nature Communications, could lead the development of treatment approach, which produces an immediate, robust and long-lasting therapeutic effect on pain symptoms.