Researchers have discovered a previously unknown way in which proteins interact with one another and cells organize themselves. This new mechanism involves two fully unstructured proteins forming an ultra-high-affinity complex due to their opposite net charge. Proteins usually bind one another as a result of perfectly matching shapes in their three-dimensional structures.
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While cervical cancer has significantly decreased in the U.S., it is still the second most common cancer in women who live in less developed countries, according to the WHO. Women in sub-Saharan Africa (SSA) have the largest age-standardized incidence and mortality rates of this potentially preventable and non-communicable disease due to the difficulty in implementing prevention, screening, and treatment programs.
A relatively inexpensive 3-D-printed model of a patient's blood vessels is as effective as current models for training medical students in interventional radiology vascular access, according to a study presented at the Society of Interventional Radiology's 2018 Annual Scientific Meeting.
In a study conducted at The University of Texas at Dallas, researchers have demonstrated a method to accelerate motor skill recovery after a stroke by helping the brain reorganize itself more quickly.
The mixed-methods study of a health system intervention for improving equitable access to medicines for diabetes and hypertension in Karnataka carried out from 2013 to 2016. Researchers use the Access to Medicines framework developed by Bigdeli et al. to assess health system preparedness for addressing diabetes and hypertension at the primary health center (PHC) level in a south Indian district.
They do this through an assessment of supply and demand side factors that influence utilization of services at government PHCs for diabetes and hypertension using data from quantitative surveys, focus group discussions (FGDs) and in-depth interviews.
Breast cancer patients reported fewer moderate or marked side effects if they were treated with radiotherapy to part of the breast or a reduced dose to the whole breast, rather than with standard radiotherapy to the whole breast, according to a study presented at the 11th European Breast Cancer Conference.
Multimodal pain management is associated with fewer perioperative complications, less opioid use and shorter hospital stays, according to a database study of more than 1.5 million joint replacements.
In this study, researchers examined the lethal disease in humans , Middle East respiratory syndrome (MERS) is a lethal disease in humans, caused by a coronavirus (MERS-CoV). It was first identified in man in 2012, in the Arabian Peninsula. The main MERS-CoV reservoir species is the dromedary, which is found in large numbers in many African countries. The study was published in the journal PNAS .
According to the study maternal alcohol use early in the pregnancy by the mother may be a risk factor for a condition in which an infant's intestines develop outside the abdomen
People with Alzheimer’s have a higher production rate of tau proteins than healthy individuals, according to a study published in Neuron. Researchers found that tau production and secretion from nerve cells appears to be an active process in the natural course of Alzheimer's disease.
According to study, researchers described a randomized controlled trial conducted in Iran. Patients with type 2 diabetes randomly assigned to twice-daily cinnamon supplementation for three months experienced a marked improvement in BMI and glycemic and lipid profiles vs. similar patients assigned to placebo.
According to the research, bioequivalent doses of oral corticosteroids are a cheaper and effective alternative to intravenous corticosteroids for acute optic neuritis (ON)