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[18F]Fallypride Characterization in Parkinson's Disease

Researchers examined regional [18F]fallypride binding in a large cohort of Parkinson's disease(PD) patients and age-matched healthy control (HC) subjects in order to simultaneously determine differences in striatal and extrastriatal D2/3 BPND, with the goal of providing cortical and subcortical binding potentials that can be directly compared. As a secondary objective, we assessed if D2/3 BPND reflected motor severity in PD patients.