The study is to differentiate Procedure sedation and analgesia (PSA) and Hematoma block(HB) for adult and pediatric patients during reduction of displaced distal radius fracture to identify the level of pain relief, the frequency of adverse effects (AEs), and reduction failure. Procedure sedation and analgesia (PSA) is often used to alleviate discomfort and to facilitate fracture reduction for patients with distal radius fracture in emergency departments and clinics, but risks of respiratory distress and needs for different levels of monitoring under PSA.
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Researchers examined the association of house-dust endotoxin with chronic bronchitis or emphysema (CBE) suggestive of COPD in a large sample representative of the U.S. population using the National Health and Nutrition Examination Survey (NHANES). The topic is of public health interest given the ubiquity of endotoxin in our environment and the high morbidity of chronic obstructive pulmonary conditions in the United States.
Researchers at the Washington State University suggest that self-managed healthcare technology should consider chronic disease patients’ values. Helping patients better manage their own health is a crucial goal-both medically and economically-but that goal will require healthcare technologies that are sensitive to patients' values.
From 2011 to 2014, there were decreases in red blood cell (RBC) and plasma transfusions among hospitalized patients, according to a research letter published in the issue of the Journal of the American Medical Association.
Literature suggests benefits of a multi-tiered approach where by intervention modalities are combined: generalized, school- or community-wide interventions with targeted components for high-risk individuals and their families. The present study aimed to evaluate the feasibility, acceptability, and outcomes of a combined school- and family-based intervention for child behavior problems in rural Nepal.
Researcher determines that a single high-fat milkshake, with a fat and calorie content like some enticing restaurant fare, can quickly transform our healthy red blood cells into small, spiky cells that wreak havoc inside our blood vessels and help set the perfect stage for cardiovascular disease. The study was published in the journal Laboratory Investigation.
Recent findings suggest a novel positron emission tomography (PET) imaging approach determining epidermal growth factor receptor (EGFR) mutation status for improved lung cancer patient management. The findings are published in the issue of Science Translational Medicine.
Researchers from the Monash University have discovered a way to the gonorrhea bacterium cleverly evade the immune system – opening up the way for new therapies that prevent this process, allowing the body's natural defenses to kill the bug. The study findings were published in the journal PLOS Pathogens.
A Phase I clinical trial testing the safety of vaccines that might have the potential to prevent HIV infection will begin this month at four sites in the U.S., marking the latest step in a three-decade quest at UMass Medical School to harness the power of DNA vaccines in addressing a major global health threat. The study would also monitor the vaccine's ability to create an immune response against HIV. It is being run by the HIV Vaccine Trials Network (HVTN).
Teen boys in the United States are less likely than girls to be vaccinated against human papillomavirus (HPV) because many doctors do not recommend the shots to boys' parents, researchers say.
Repurposing a class of antitumor compounds called HDAC inhibitors, already approved by the FDA for the treatment of diseases such as leukemia, provides a new therapeutic approach for ovarian cancer with mutations in the ARID1A gene, according to a study published in the journal Cell Reports.