The study exhibits the epidemiological data; researchers demonstrate the value of estrogen supplementation from the onset of menopause. They also show that only one of the three estrogen receptors seems to be involved in this mechanism. This could ultimately provide more targeted therapies. An explosion of type 2 diabetes cases for women after menopause. The study was published in JCI Insight.
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In a study published in Nature Neuroscience, a team of American scientists at Beth Israel Deaconess Medical Center (BIDMC) has demonstrated the circadian clocks may regulate the aggressive behaviors of male mice, opening the door to potential opportunities for managing the evening-time agitation common in patients with degenerative neurological disorders.
One of the major challenges identified by the WHO in efforts to eradicate the hepatitis C virus (HCV) is the diagnosis of chronic cases that are asymptomatic. The new screening assay allows the beginning of the treatment as soon as diseases are diagnosed.
The treatment landscape in advanced melanoma is changing dramatically with the approval of new drugs. Vemurafenib was the first approved targeted agent for the treatment of BRAF-mutant advanced melanoma. However, treatment with a BRAF inhibitor is linked with acquired resistance occurring in half of the patients after approximately six months. Combination of MEK and BRAF inhibitor therapy results in extension of the time to resistance, translating into longer overall survival of treated patients.
According to a study, researchers examine that physical activity helps to prevent a high genetic risk for heart disease still works to keep your heart healthy. In one of the largest observational studies on fitness and heart disease, researchers examined data collected from nearly a half-million people in the UK Biobank database. The study was published in Circulation.
A new study published in the journal Psychology Research and Behavior Management suggests that yoga and other mindfulness-based practices at school helps third-graders exhibiting stress and anxiety improve their wellbeing and emotional health.
Marine-originated compounds have gained great interest as anticancer agents. Gliotoxin (GTX) is a secondary metabolite isolated from the marine-derived fungus Aspergillus fumigatus. GTX showed potential therapeutic agent against chemoresistant cancer cells.
Researchers aimed to study distinct aspects of human monocyte-derived macrophage (MDM) activation by human corneal tissue as a possible initial stage in human corneal allograft rejection. This in vitro approach allows to characterize cellular responses in a well-defined setup and may serve as a valuable complement to current animal models.
A study focused on an Enzyme; Researchers examined the enzyme in gram-negative bacterium Pseudomonas aeruginosa, a pathogen that causes pneumonia and sepsis. Beta-lactam antibiotics, including penicillin, are one of the most widely used classes of antibiotics in the world. Though they have been in use since the 1940s, scientists still don't fully understand what happens when this class of drugs encounters bacteria. The study was published in the Proceedings of the National Academy of Sciences.
Internists and nurse practitioners were more likely than family physicians to intensify glycemic treatment in older patients in a way that was inconsistent with American Diabetes Association (ADA) guidelines.
Adding the drug trastuzumab with the chemotherapy regimen of women with a rare form of uterine cancer lengthens the amount of time their tumors are kept from growing, according to the research
This year's flu vaccine has been less effective in protecting people from the most common strain of the virus, compared with recent years. And once people become infected with the flu, there are few good ways to treat it.
Now scientists at The Scripps Research Institute have discovered a new aspect of the flu virus and how it interacts with antibodies in the lungs. This research could lead to a new approach for developing vaccines to prevent the flu, as well as novel treatments for people who are already infected. The study is being published today in the journal Cell Reports.