All news from Anaesthesiology

Inhibiting Fibronectin Might Prevent Heart Failure

Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure. Researchers are testing a manufactured peptide called pUR4 to block the fibronectin protein in human heart cells donated by heart failure patients. The study was published in the journal Circulation.

Novel Precision Cancer Model Opens Doors for Cancer Therapies

An extremely powerful and versatile mouse model of cancer, developed by the researchers from the Seve Ballesteros Foundation-CNIO Brain Tumour Group at the Spanish National Cancer Research Centre (CNIO), will improve cancer research and accelerate pre-clinical testing of novel targeted therapies, a new study published in Nature Communications reports.