According to a new study, researcher determine that physician assistants (PAs) are increasingly used in dermatology practices to cut costs and improve access to care, but are more likely than dermatologists to perform unnecessary skin biopsies to check for cancer, while being less likely to accurately diagnose early stage skin cancers. The study was published in JAMA Dermatology.
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The researcher demonstrated that negative PaCO2–ETCO2 differences (i.e. ETCO2 reading higher than PaCO2) can occur in pediatric patients undergoing general anesthesia after tracheal intubation with a cuffed tube and mechanical ventilation. The results of this large study (799 patients and 2452 measurements) differ from previous work in this area.
For instance, they found an overall mean arterial to ETCO2 difference of −0.18 kPa, with 71.2% of samples showing a negative difference, compared with Goonasekera et al. who found a mean PaCO2– an ETCO2 difference of +0.66 KPa, with only 22.7% of samples demonstrating a negative PaCO2– ETCO2. Researcher attributes the high proportion of negative values they obtained to an incorrect measurement setting in the apparatus used for gas analysis and capnography.
Ketamine has been found to be effective in refactory depression. The researchers have developed a nasal spray formulation of ketamine that could help alleviate symptoms of major depression and suicide thoughts, according to a study published in The American Journal of Psychiatry (AJP).
The US Drug Enforcement Administration (DEA) arrested 28 prescribers and pharmacists and revoked 147 licenses of individuals who handle controlled substances. The actions were taken as part of the agency's ongoing efforts to combat the opioid epidemic.
According to a study, researchers investigate the forces applied to the mandible by the masticatory muscles, is of considerable importance from clinical, anthropological and evolutionary perspectives. The Purpose of this study is to identify the relation between masticatory muscle force and mandibular shape and to relate variations in specific muscle CSAs to particular aspects of mandibular shape and size variation.
Head CT scans of 382 adults were utilized to measure masseter and temporalis muscle cross-sectional areas (CSA) as a surrogate for muscle force and 17 mandibular anthropometric measurements. The association between shape and muscle CSA (controlled for size) was assessed using two-block partial least squares analysis. Correlations were computed between mandibular variables and muscle CSA (all controlled for size).
Cancer Australia has launched a Framework to improve the outcomes and experiences of people suffering from lung cancer – the leading cause of cancer death in Australia.
A new study by UCSF researchers using techniques drawn from computational biology could make it much easier for physicians to use the genetic profile of a patient's tumor to pick the chemotherapy treatment with the fewest side effects
Many European countries lack a comprehensive policy to eliminate viral hepatitis as a major public health threat, according to a patient group-based survey implemented in 25 countries. The Hep-CORE study was coordinated by ISGlobal – an institution supported by the "la Caixa" Foundation – and led by the European Liver Patient's Association.
Scientists at UT Southwestern Medical Center have identified a protein that is strongly associated with aggressive breast cancer and could be a target for future therapies to treat the deadly disease.
The findings, published in the Journal of Clinical Investigation, suggest that high levels of the protein ZMYND8 could be correlated with poor survival in breast cancer patients.
Research finds, a tiny layer of graphene flakes becomes a deadly weapon and kills bacteria, stopping infections during procedures such as implant surgery
While women are two to four times more likely than men to tear the anterior cruciate ligament (ACL) in their knee, the cause of this injury is no difference between the sexes, according to new research from Duke Health.
Italian researchers have developed a novel method, based on magnetic resonance imaging (MRI), to assess the tumor status without taking tissue samples. The technique, reported in the journal Angewandte Chemie, measures proton nuclear resonance dispersion profiles at low magnetic fields, which reveals the water exchange rate of the tumor cells.