All news from Anaesthesiology

New Vaccines To Treat Opioid Abuse And Prevent Fatal Opioid Overdoses

Researchers from the University of Minnesota Medical School and Minneapolis Medical Research Foundation at Hennepin Healthcare is developing vaccines against heroin and prescription opioids, such as oxycodone and fentanyl. These vaccines function by using the immune system to produce molecules (antibodies) that target, bind, and prevent opioids from reaching the brain (the site of drug action). Heroin and prescription opioid abuse and fatal overdoses are a public health emergency in the United States. Vaccines offer a potential new strategy to treat opioid abuse and prevent fatal opioid overdoses.

High-Decibel Music Leads To Short-Term Hearing Loss

A New Study examines that drinking does not help matters, with drunk concertgoers moving closer to loudspeakers. High-decibel music blasting at big concert venues is a known cause of short-term hearing loss. The study of 51 young attendees at an outdoor music festival in the Netherlands found that "when participants consumed more alcohol, they exhibited more dangerous behaviour" tied to hearing loss. The study was published in JAMA Otolaryngology-Head & Neck Surgery.

A Unique Protein Can Target For The Development Of New Drugs

Over a thousand people die from malaria every day. The disease is caused by a single-cell parasite (protozoan) that is transmitted by mosquitoes. The malaria parasite is highly dependent on a unique protein for infecting new mosquitoes. This protein could be a target for the development of new drugsAnti-malaria efforts currently focus on effective diagnostics, mosquito nets, insecticides and drugs. Additionally, a strong effort is being made at Radboud university medical centre and other institutes to develop a vaccine.

Compare The Effects Of Two PAP Warm-Up Strategies On The RSA Of Soccer Players

A study compared the effects of a traditional warm-up with two post-activation potentiations (PAP) warm-up strategies on the repeated sprint ability (RSA) of soccer players from national (NL) and regional (RL) competitive levels. Sixteen young players were recruited to complete a traditional warm-up, a PAP warm-up incorporating squats with a load (~60% 1RM) that allowed a high speed (1 m/s) of movement and a high number of repetitions (PAP-1), and a PAP warm-up with a load (~90% 1RM) that allowed a moderate speed (0.5 m/s) of movement and a reduced number of repetitions (PAP-0.5).