Researchers have made the surprise discovery that the 'odd one out' in a family of proteins known to drive cancer development is instead critical for preventing stomach cancers. The research team showed switching off a gene called NF-κB1 caused the spontaneous development of stomach cancers, driven by chronic inflammation. The study also revealed that immunotherapy may prove to be a significant tool for treating stomach cancers that are driven by runaway inflammation, warranting further investigation. The study was published in the journal Immunity.
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Scientists at the National Institute of Allergy and Infectious Diseases (NIAID) have developed cynomolgus macaque model to study the Crimean-Congo hemorrhagic fever. The discovery was reported in the journal Nature Microbiology.
Management of symptomatic lumbar spondylolysis without listhesis in adolescent athletes represents a unique challenge for the treating physician. In the general population, the majority of cases can be successfully treated with rest and conservative management. Surgical intervention is indicated only for those few individuals who have failed a prolonged (>6 months) trial of conservative management.
Marine Omega-3 polyunsaturated fatty acids (n-3 PUFA) are important nutrients during periods of rapid growth and development in utero and infancy. Maternal health and risk factors play a crucial role in birth outcomes and its cardio-metabolic health.
With the National Health Mission (NHM) top leadership initiating the National Health Protection Scheme (NHPS) within the Ayushman Bharat programme, India has moved one more step closer to successfully transcending the so-called supply-side versus demand-side dualism in the health sector.
A study evaluated the prevalence, risk factors, and prognosis of fungal infections in adults on ECMO. Patients on extracorporeal membrane oxygenation (ECMO) are often among the most severely ill in the intensive care unit. They are often receiving broad-spectrum antibiotics; they have multiple entry points for pathogens, and their immune system is impaired by blood circuit interaction. These factors are thought to predispose them to fungal infections.
Peter LaMont's second child will be born next month, but the last time he put an infant to bed was 16 years ago. So, the Bridgewater father turned to the SIDS Center of New Jersey's new SIDS Info app to catch up on safe sleep recommendations for babies.
Royal Education Council (REC) in Bhutan asked schools to consider ways to reduce the burden of heavy bags carried by students. Since a survey led by the REC found that Bhutanese students were found carrying bags weighing five kg – 10kg, which is in contravention to the recommended load.
According to a study, researchers estimated that Doravirine, an investigational non-nucleoside reverse transcriptase inhibitor (NNRTI), is as effective as ritonavir-boosted darunavir, a protease inhibitor, in treatment-naive adults infected with HIV-1. "Doravirine may be an option for people with HIV who are treatment naive. "Doravirine addresses the disadvantages of current NNRTIs that caused them to be demoted as preferred or recommended treatment options.
Allogeneic blood transfusion-related immunomodulation may relatively suppress the immune system. This systematic review seeks to determine if allogeneic blood transfusion increases the risk of postoperative infection.
Researchers highlighted the renal impact of a ciprofloxacin overdose, and thus conducted a prospective study in the Department of Nephrology at La Rabta Hospital between 2010 and 2015