All news from Anaesthesiology

MS Drug Could Reduce Painful Side Effects of Common Cancer Therapy

Researchers from the Saint Louis University School of Medicine have discovered why many cancer patients experience severe pain when treated with the anticancer drug bortezomib. The study, to be published in the Journal of Experimental Medicine, suggests that a drug already approved to treat multiple sclerosis could mitigate this effect, allowing myeloma patients to successfully complete their treatment and relieving the pain of myeloma survivors.

Bacteria Boost Antifungal Drug Resistance in Severe Childhood Caries

A new study from the University of Pennsylvania found that early childhood caries result from dental plaque that contains both bacteria and fungus working together to make the biofilm on the teeth more pathogenic and difficult to remove. Now they have shown that these two types of microorganisms synergize to enhance drug resistance, enabling the fungal cells to avoid being killed by antifungal therapies. Yet simultaneously targeting the matrix produced by the bacteria along with the fungus offers a way around this protection.