All news from Anaesthesiology

Couple Bridged Peptides Bind To Disease Targets

A study developed a new type of 'double-bridged peptide' that can be tailored to bind tightly to disease targets of interest. The peptides' highly efficient binding, combined with their small size and high stability make them ideal for drug therapies. Peptides are short chains of amino acids that can bind to proteins and change their function. They show a high binding affinity, low toxicity, and are easy to synthesize, all of which makes peptides ideal for use in drug development, and many naturally occurring peptides such as insulin, oxytocin, somatostatin and the antibiotics vancomycin or polymyxin B, are already successfully used like that.

Risk Of A Drug Overdose In Adolescents And Young Adults

A team of researchers have identified factors that may increase the risk of a drug overdose in adolescents and young adults. They describe finding that more than a quarter of those seeking treatment at Addiction Recovery Management Service, an MGH-based outpatient substance-use-disorder treatment program for youth ages 14 to 26, had a history of at least one overdose. Factors associated with increased overdose risk were disorders involving the use of alcohol, cocaine or amphetamines and histories of depression, anxiety or eating disorders. The study was published online in the Journal of Clinical Psychiatry.

Lack of Knowledge of Inhaler Devices Use among COPD Patients, New Findings

Inhaled medications play an important role in treating chronic obstructive pulmonary disease, or COPD, and it is imperative that the inhaler device be used properly to effectively treat the disease.

However, in a recently released study in the Journal of the COPD Foundation, researchers found that healthcare providers and patients prioritize medication over the device when selecting treatments, showing limited concerns about proper device use.

Cholera Outbreaks Seen In Haiti

According to campaigners accusing the global community of again failing the Caribbean nation. Haitians battling cholera blamed on United Nations peacekeepers are getting little support with only two percent of promised funds materializing, Haiti was free of cholera until 2010 when peacekeepers helping after a devastating earthquake that killed more than 250,000 people accidentally dumped infected sewage into a river. 

Bionic Suit: Paralyzed Patients Benefited

Patients undergoing physical rehabilitation at Rush for paralyzing injuries are being aided by a robotic suit designed to help raise people to full height and walk.Rush is the only medical centre in Chicago and one of only 98 facilities in the world offering the EksoGT robotic exoskeleton device for clinical therapy for both inpatients and outpatients.

Exendin-4: Cocaine Relapse Reduced

Cocaine and other drugs of abuse hijack the natural reward circuits in the brain. In part, that is why it is so hard to quit using these substances. Moreover, relapse rates hover between 40 and 60%, similar to rates for other chronic conditions like hypertension and Type 1 diabetes.