All news from Anaesthesiology

Repeated Exposures To Anesthesia Affect Learning And Attention

According to a new study, researchers examined children with multiple exposures to anaesthesia before age three are more likely to develop adverse outcomes related to learning and attention. The study was published in Anesthesiology. They identified a cohort of children born between 1996 and 2000. Propensity matching selected children based on exposure or non-exposure to general anaesthesia before age 3. This identified 116 children multiply exposed, 457 singly exposed, and 463 unexposed children.

Wearable Biosensing Devices Use in Measuring Sweat

When people sweat, they unknowingly release a wide range of chemicals that can noninvasively inform clinicians on anything from stress hormone levels to glucose. An international team of researchers recently developed a new membrane that mitigates both issues that arise from direct dermal contact and sweat dilution for sweat biosensors. The membrane performs hundreds of times better than other methods and holds up to repeated use.

Cryo-electron Microscopy Images Reveals Drug-Target Sites

A study estimates that researchers discovered telomerase, an enzyme that lengthens chromosome ends and prevents them from fraying enough to kill a cell, speculation ran wild about its role in ageing and cancer, setting off a full-court press to produce drugs to activate or block the enzyme. Cryo-electron microscopy images reveal details of protein, RNA binding and possible drug-target sites. The study was published in the journal Nature.

Anatomy Of Cranial Nerve Foramina Of The Anterior And Middle Fossa

The study is focused on the foramina of the anterior and middle cranial fossae, discussing each foramen’s shape, orientation, size, surrounding structures, and structures that traverse them. Cranial nerve foramina are integral exits from the confines of the skull. Despite their significance in cranial nerve pathologies, there has been no comprehensive anatomical review of these structures. Furthermore, by comparing the size of each foramen against the cross-sectional areas of its contents, they estimate the amount of free space in each. They also review lesions that can obstruct the foramina and discuss their clinical consequences.

Reprogramming Ordinary Cells Into Healthy Heart Muscle Cells

A study has created new healthy heart muscle cells within a patient's own ailing heartScientists have reprogrammed ordinary cells called fibroblasts into new and healthy heart muscle cells and recorded changes that appear to be necessary for this reprogramming. The reprogrammed ordinary cells called fibroblasts into new and healthy heart muscle cells and recorded changes that appear to be necessary for this reprogramming. The study was published in Cell Reports.

Marijuana Could Significantly Reduce The Chronic Pain

A study estimates that researchers report show up to 65% of older adults who use medical marijuana significantly reduced their chronic pain and dependence on opioid painkillers. A questionnaire of older men and women suffering from chronic pain who were given medical marijuana found that the drug significantly reduced pain and their need for opioid painkillers.