All news from Anaesthesiology

Developing Neocortex Neurons Undergoes Morphological Changes In Brain

Researchers have found that developing neocortex neurons in mammals undergo a morphological transition from a multipolar shape to a bipolar shape due at least partially to signaling in neuronal migration during brain development. They used to study the process by which the neocortex develops in mammals and what they found. The study was published in the journal Science.

Optical Microscopy Can Visualize Ultra-High-Resolution Images

Researchers have developed a novel method for optical microscopy. Using biological motors and single quantum dots, they acquire ultra-high-resolution images. The resolution of conventional optical microscopy is limited by the fundamental physical principle of diffraction to about one half of the wavelength of the light: If the distance between two objects is smaller than this so-called "diffraction limit," they can no longer be visually separated their image appears "blurred ."

To acquire optical images at the scale of few nanometers, this is clearly not sufficient. The study was published in the journal Nature Nanotechnology. In a new study, physicists from the Julius-Maximilians-Universität Würzburg (JMU) and the Technische Universität Dresden now show that it is possible to measure these near-fields with significantly less effort. They used a biomolecular transport system to slide many extremely small optical nano-probes over a surface.

Analysis Showed That Patients With Atrial Fibrillation

The AVIATOR 2 is a multicenter prospective observational study of patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) in 11 international sites. The use of a novel smartphone-based survey was used to capture physician and patient perspectives regarding antithrombotic therapies (ATT) after PCI. Results of the AVIATOR 2 international registry are being presented as late-breaking clinical science at the Society for Cardiovascular Angiography and Interventions (SCAI) 2018 Scientific Sessions.

A Small Molecule Blocks The Transfer Of Tau Aggregates From Cell To Cell

Researchers have observed a promising drug strategy that blocks tau transmission. Alzheimer's disease destroys brain cells in part by promoting the formation of insoluble clumps that contain a protein called tau. Not only are these "tau aggregates" toxic for the cells that harbor them, but they also invade and destroy neighboring brain cells, or neurons, which speeds the cognitive decline associated with the Alzheimer's. The study was published online in the journal Biochemical and Biophysical Research Communications.