Researchers tissue-engineered human pancreatic islets in a laboratory that develop a circulatory system, secrete hormones like insulin and successfully treat sudden-onset type 1 diabetes in transplanted mice.
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Nancy Schoenborn, M.D., assistant professor, Johns Hopkins University School of Medicine and colleagues conducted three qualitative studies that set older adults at the lead for a better conclusion of how they prefer to discuss various health topics.
According to study, researchers determine that probiotics are effective for preventing Clostridium difficile infection (CDI) in patients treated with antibiotics. Probiotics are considerably more effective in settings where the risk for Clostridium difficile infection is moderate to high. The study was published in Infection Control.
Idiopathic pulmonary fibrosis (IPF) is one of the most challenging and frustrating diseases that pulmonologists face. And despite affecting 1 out of 200 adults over the age of 65 in the United States, general awareness of IPF is low.
Asking emergency department (ED) providers to self-identify their opioid prescribing practices and then providing them with timely, clinically relevant, individualized, and actionable feedback on their actual opioid prescribing data, significantly decreases future opioid prescribing among providers who underestimate their baseline prescribing. The study was published in the journal Academic Emergency Medicine (AEM).
According to a new study, researchers examine infants who are diagnosed with drug withdrawal after birth who are treated with medication as outpatients at home are treated three times longer than infants treated solely as inpatients. The study, Outpatient Pharmacotherapy for Neonatal Abstinence Syndrome, also found that the infants with NAS treated as outpatients were more likely than their inpatient counterparts to have more repeat visits to the emergency room in the six months post-discharge. The study was published in The Journal of Pediatrics.
According to study, researchers experimented on mathematical models to re-enact the complex process of brain development that occurs as initializing cells(progenitor cells), they start to grow and begin to differentiate into more specialist cells at various points in time. The study was published in the journal Cerebral Cortex.
Mutations driving cancer development leave behind specific 'scars,' so-called mutational signatures, in the genome. In principle, they allow for profiling of the cancer type and its development — but the noisy environment of a cancer genome makes correlations difficult. Using CRISPR-Cas9 technology, researchers were able to show for the first time that specific genetic alterations indeed lead to the predicted mutational signatures observed in human cancers.
Researchers found that lesbian and bisexual women participating in a major longitudinal study have a greater incidence of type 2 diabetes than heterosexual participants, and higher BMI explained this association. In a newly published study involving 94,250 women across the United States, researchers found that lesbian and bisexual (LB) women were more likely than heterosexual women to develop type 2 diabetes during the course of the 24-year study follow up.
They investigated the incidence of type 2 diabetes in lesbian and bisexual women and heterosexual women in a large, longitudinal U.S. cohort. The study was published in Diabetes Care. For the study, the team analyzed survey results dating back to 1989 from women participating in the Nurses' Health Study II, which is one of the largest investigations into the risk factors for major chronic diseases in women.
A study analyzed that the personal perceptions and experiences of patients, families, and healthcare professionals have highlighted the need for improvement in symptom management for end of life care. They identified several areas of treatment which were often perceived as sub-optimally managed by healthcare professionals, including; pain, breathing difficulties, nutrition, and hydration. Nutrition and hydration were specifically recognized as being "of significant concern," particularly for carers.
Risk of myocardial infarction (MI) is increased in patients with spondyloarthritis (SpA) who use the nonsteroidal anti-inflammatory drug (NSAID) diclofenac but not in those who take naproxen, researchers say.