Macrophages are key players in the pathogenesis of large-vessel vasculitis (LVV) and may serve as a target for diagnostic imaging of LVV. The radiotracer, 18F-FDG has proven to be useful in the diagnosis of giant cell arteritis (GCA), a form of LVV
The rising incidence of sepsis, a leading cause of in-hospital death, has prompted the Centers for Medicare and Medicaid Services (CMS) to issue protocols known as care bundles to standardize and improve sepsis care. Because of a known association between elevated lactate levels and increased mortality, the guidelines mandate that lactate levels should be tested soon after the onset of sepsis.
According to a new study, researcher examined the 2014 outbreak of Ebola virus disease (EVD) in West Africa was the largest in history. Starting in September 2014, International Medical Corps (IMC) operated five Ebola treatment units (ETUs) in Sierra Leone and Liberia. They reveal daily usage rates for disinfectant and personal protective equipment, informing future outbreaks. The study was published in the journal PLOS ONE.
Scientists have developed a lab-based system for studying the most common type of liver disease, paving the way for research into new therapies. The team has devised a way to probe Non-Alcoholic Fatty Liver Disease.
Visual acuity outcomes after anti-vascular endothelial growth factor (anti-VEGF) treatment for choroidal neovascularization (CNV) are better in fellow eyes of previously treated patients with neovascular age-related macular degeneration (nvAMD), according to a retrospective study
The U.S. Food and Drug Administration today approved Palynziq (pegvaliase-pqpz) for adults with a rare and serious genetic disease known as phenylketonuria (PKU). Patients with PKU are born with an inability to break down phenylalanine (Phe), an amino acid present in protein-containing foods and high-intensity sweeteners used in a variety of foods and beverages. Palynziq is a novel enzyme therapy for adult PKU patients who have uncontrolled blood Phe concentrations on current treatment.
National guidelines assume that all patients who're diagnosed with clinical sepsis in an emergency department will be admitted to the hospital for additional care, but new research has found that many more patients are being treated and released from the ED for outpatient follow-up than previously recognized.
A potential new drug to treat the common cold prevents rhinoviruses and other picornaviruses from gaining a toehold in human cells, according to findings published in Nature Chemistry. Researchers have developed "broad-spectrum antipicornaviral drug."
The US Food and Drug Administration (FDA) approved computer-aided detection and diagnostic software called OsteoDetect to speed the diagnosis of wrist fractures in adults, the agency announced yesterday
A new discovery about how the immune system responds to common sinus infections and asthma could explain why patients develop these issues in the first place and ultimately may lead to improved targeted therapies. Researchers have identified the source of the inflammatory cytokine Interleukin-25 (IL-25), an immune molecule that recruits a subset of inflammatory cells.
Common respiratory disorders like chronic rhinosinusitis and asthma have recently been linked to elevated levels of IL-25, but the cellular source of it in the respiratory system was unknown until now. The study findings are published in the Journal of Allergy and Clinical Immunology
According to a study, researcher evaluates teenage girls encouraged to reduce their skin cancer risk by protecting themselves from harmful UV rays. As Memorial Day signals the unofficial start of summer, many teen girls will be eager to get out of school and spend time outside and some may want to get a tan. But a new public service advertisement from the American Academy of Dermatology encourages those who are thinking of tanning to think again.
Women with a large preoperative genital hiatus that were not surgically normalized after native tissue vaginal vault suspensions are at risk of prolapse recurrence or retreatment, researchers say. They are at higher risk of anatomic failure.