All news from Anaesthesiology

Adult Life Lost To High Insulin Prices

People with type 1 diabetes was diagnosed and because of the costs, they lost the life because they couldn't afford the exorbitant price of his life-saving insulin. As they had a full-time job that didn't offer health insurance. But because he was working full-time, he didn't qualify for subsidies under the Affordable Care Act. The insurance he could get, the premium and the deductible were so high, he couldn't afford to pay for a policy. His deductible would've been $7,600.

Recycling Of An Cellular Process Can Extend The LifeSpan

Researchers have determined that "cellular housekeeping" can extend the lifespan and healthspan of mammals. They found that mice with persistently increased levels of autophagy in the process a cell use to dispose of unwanted or toxic substances that can harm cellular health live longer and are healthier. The study was published in Nature.

New Way To Block A Root Cause Of Pain

Researchers have found a new way to block a root cause of pain. The key is a naturally occurring protein called apolipoprotein A-I binding protein (AIBP). AIBP binds to toll-like receptor 4 (TLR4), a protein that sits on the surface of cells like an antenna, searching for signs of infection or tissue damage. The researchers found that treating mice with a single spinal injection of AIBP and thus switching TLR4 "off" prevented and reversed inflammation and cellular events associated with pain processing. The study was published in Cell Reports.

New Insights into Tumor Cell Mechansim

Greater knowledge of the mechanisms that contribute to the survival of tumour cells is key to vanquishing them. The study published in the journal Cancer Cell reveals a new protective mechanism for tumour cells in breast cancer and identifies novel therapeutic targets to treat this condition.