All news from Anaesthesiology

Mutations in the Ebola Virus Makona Genome and Pathogenecity

Early during the West African Ebola epidemic, scientists speculated that the genetic diversity of the Makona strain of virus (EBOV-Makona) would result in more severe disease and more transmissibility than prior strains. However, scientists have determined that certain mutations stabilized early during the epidemic and did not alter Ebola disease presentation or outcome. Their work offers evidence to support previous findings that the diversity of EBOV-Makona did not significantly impact the course of the disease.

Individual Cells Organize To Form Multi-layered Structures Of Embryo

Researchers have demonstrated the ability to program groups of individual cells to self-organize into multi-layered structures reminiscent of simple organisms or the first stages of embryonic development. A complex biological structures, an eye, a hand, a brain emerge from a single fertilized egg. This is the fundamental question of developmental biology, and a mystery still being grappled with by scientists who hope to one day apply the same principles to heal damaged tissues or regrow ailing organs. The study was published in Science.

New Microscopy That Observes The Evolution Of Cell Membrane Focal Adhesions

Researchers have developed a new form of microscopy that allows them to observe the formation and evolution of cell membrane focal adhesions. Focal adhesions are large specialized proteins that are located in the area where a cell membrane meets the extracellular matrix (ECM), a collection of molecules surrounding the cells that provide support and regulate micromechanical signals to the cells.The study was published in Light: Science & Applications.

RFID Chips Aid in Tracking Biological Samples

Researchers want to use radio frequency identification (RFID) chips for keeping track of organoids, samples of human tissue that mimic pieces of organs and are grown from stem cells. The organoids the researchers embedded with RFID chips functioned normally and withstood extreme conditions, suggesting that they could be a useful way to organize and identify the large quantities of organoids needed in experimental situations.