Virtual colonoscopy (CT Colonography) – shown to increase colorectal cancer screening rates at a lower cost than standard colonoscopy – can help jump-start the transition to screening Americans starting at age 45 as new American Cancer Society Screening guidelines recommend.
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Researchers determined nearly two-thirds of caregivers whose loved ones suffer from the debilitating effects of Alzheimer's or related dementia say they would take medication to delay the onset of their own memory loss by even six months if it were affordable and free of side effects. Sixty-four percent say they've already made healthy lifestyle modifications in an effort to prevent their own memory loss, making meaningful edits to their diet and exercise. However, only one-third of caregivers say they have been tested for the Alzheimer's gene.
Most patients with advanced non-small cell lung cancer (NSCLC) can now avoid having chemotherapy as a first-line treatment after a large, randomized trial showed that immunotherapy with the programmed cell death ligand 1 (PD-L1) blocker pembrolizumab (Keytruda, Merck) is effective even in patients with minimal PD-L1 expression.
A new study of decision-making about the use of antibiotics in medicine has found that the mistaken belief that antibiotics are harmless is widespread, especially among patients. Clinicians and patients alike are influenced by the general notion of "why not take a risk" ("WNTAR")
According to a study, researchers suggest that nail treatments such as acrylic nails or nail polishes do not, as previously thought, affect readings from digital pulse oximetry (DPO) devices used to monitor patients' blood oxygen saturation (SpO2) levels in hospital.
De novo generation of cartilage within cryopreserved aortic allografts has been observed recently. This process originated from the recipient cells, which was observed in animal models.
Moreover, remaining viable matrix cells have been identified to play a critical role in the regenerative process as a way to release proangiogenic, chemoattractant, pro-inflammatory or pro-immunomodulatory cytokines, and growth factors.
This prospective study was designed to evaluate the feasibility of airway bioengineering using stented cryopreserved aortic allografts as biological matrices.
A new approach pioneered at the University of Pennsylvania's Abramson Cancer Center may provide a new path towards treating Acute Myeloid Leukemia (AML) with CAR T cells. To treat AML, investigators have to target a specific protein, CD33
A study examines that Biochemists have determined the detailed structure of a volume-regulated chloride channel. This cellular valve is activated in response to swelling to prevent the cell from bursting. The protein also plays an important role in the uptake of chemotherapeutics and the release of neurotransmitters after a stroke. The controlled regulation of its activity thus opens up a promising strategy for novel therapies.
Diabetes in pregnant women can have serious health consequences for both mother and baby, and the U.S. Centers for Disease Control and Prevention (CDC) has identified four target areas in which increased surveillance, screening, and preventive care can improve maternal and infant health
A rare opportunity to analyze both blood and tissue samples from human transplant recipients has allowed immunology researchers at the Babraham Institute to pinpoint how an immunosuppressive drug works to prevent the production of antibodies against the transplanted tissue.
Researchers conducted a study that reviewing the internal medical records of surgical patients who underwent mepivacaine spinal anesthesia(SA) at Toronto Western Hospital over the last decade to determine the rate of TNS. They defined TNS as new onset back pain that radiated to the buttocks or legs bilaterally. Transient neurologic symptoms (TNSs) can be distressing for patients and providers following uneventful spinal anesthesia.
KRAS is one of the most commonly mutated and widely studied genes in cancer; a quick PubMed search for KRAS and cancer turns up more than 9,000 entries. The vast majority of studies examining the gene's cancerous role focus on its mutated state. But there is more than one way for a gene to be an oncogene