All news from Anaesthesiology

Current State Of Caregiving For Alzheimer's Disease

Researchers determined nearly two-thirds of caregivers whose loved ones suffer from the debilitating effects of Alzheimer's or related dementia say they would take medication to delay the onset of their own memory loss by even six months if it were affordable and free of side effects. Sixty-four percent say they've already made healthy lifestyle modifications in an effort to prevent their own memory loss, making meaningful edits to their diet and exercise. However, only one-third of caregivers say they have been tested for the Alzheimer's gene.

Effectiveness of Pembrolizumab in Non-Small Cell Lung Cancer

Most patients with advanced non-small cell lung cancer (NSCLC) can now avoid having chemotherapy as a first-line treatment after a large, randomized trial showed that immunotherapy with the programmed cell death ligand 1 (PD-L1) blocker pembrolizumab (Keytruda, Merck) is effective even in patients with minimal PD-L1 expression.

Lung Cancer: Promising Results With New Airway Transplantation Technique

De novo generation of cartilage within cryopreserved aortic allografts has been observed recently. This process originated from the recipient cells, which was observed in animal models.

Moreover, remaining viable matrix cells have been identified to play a critical role in the regenerative process as a way to release proangiogenic, chemoattractant, pro-inflammatory or pro-immunomodulatory cytokines, and growth factors.

This prospective study was designed to evaluate the feasibility of airway bioengineering using stented cryopreserved aortic allografts as biological matrices.

Cellular Valve Swells Up And Prevents Cell From Bursting

A study examines that Biochemists have determined the detailed structure of a volume-regulated chloride channel. This cellular valve is activated in response to swelling to prevent the cell from bursting. The protein also plays an important role in the uptake of chemotherapeutics and the release of neurotransmitters after a stroke. The controlled regulation of its activity thus opens up a promising strategy for novel therapies.

Determination Of The Rates Of TNS In Surgical Patients Who Undervent Mepivacaine SA

Researchers conducted a study that reviewing the internal medical records of surgical patients who underwent mepivacaine spinal anesthesia(SA) at Toronto Western Hospital over the last decade to determine the rate of TNS. They defined TNS as new onset back pain that radiated to the buttocks or legs bilaterally. Transient neurologic symptoms (TNSs) can be distressing for patients and providers following uneventful spinal anesthesia.