According to new study, researchers examined the molecular mechanism of activation of the GPCR-arrestin complex. The effectiveness of new drugs depends crucially on a fundamental understanding of the complex processes within the cells of the body. They have deciphered an important molecular step of cellular signal transmission. Their findings could help the development of specific drugs against various diseases, such as asthma and high blood pressure. The study was published in the journal Nature.
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As word came over the radio that a Sherpa had been struck on the head by a falling rock high on Everest, the three doctors at base camp jumped into action, fully aware that saving him would be a life-or-death race against the unpredictable mountain.
The cerebral cortex—the brain's epicenter of high-level cognitive functions, such as memory formation, attention, thought, language and consciousness—has fascinated neuroscientists for centuries
A new equation for estimating future risk for cardiovascular events appears to give more accurate results than does the existing equation currently recommended and this has major implications for selecting patients eligible for statins, aspirin, and antihypertensive therapy. The study was published online in Annals of Internal Medicine.
An aqueous extract of Poria robiniophila called Huaier granule improves recurrence-free survival (RFS) and overall survival after radical surgical resection of hepatocellular carcinoma (HCC), researchers from China report.
Immunization with beneficial bacteria can have long-lasting anti-inflammatory effects on the brain, making it more resilient to the physical and behavioral effects of stress, according to new research by University of Colorado Boulder scientists.
Fluorine-18 fluorodeoxyglucose positron emission tomography with computed tomography attenuation correction (PET-CT) in myeloma can detect and enumerate focal lesions by the quantitative characterization of the metabolic activity
According to a study, researchers examined engaging in ultraviolet (UV) indoor tanning is associated with increased use of skin cancer examinations. The study was published online in JAMA Dermatology.
Macrophages, large white blood cells that engulf and destroy potential pathogens, harbor active viral reserves that appear to play a key role in impaired learning and memory in mice infected with a rodent version of HIV. Chao-Jiang Gu et al. present these new findings in PLOS Pathogens.
The increasingly popular practice of 'vaginal seeding'—in which cesarean-delivered babies are immediately swabbed with the mother's vaginal fluids—is declared unjustified and potentially unsafe in a new critical review of scientific literature