All news from Anaesthesiology

Lack Of Estrogen Leads To Memory Problems

Lack of estrogen may play a role in the development of anxiety and memory problems, according to a new rodent study. The findings will be presented today at the American Physiological Society's (APS) Cardiovascular, Renal and Metabolic Diseases: Sex-Specific Implications for Physiology conference in Knoxville, Tenn.

Improvement in Annual Lung Cancer Screening Required, Researchers Say

A study from the Thoracic Oncology Research Group (TORG), Division of Pulmonary Critical Care, Medical University of South Carolina aimed to examine the adherence to annual low-dose computed tomography (LDCT) screening after baselines LDCT within the Veteran Health Administration Lung Cancer Screening Demonstration Project (LCDSDP).

The study will be presented at the CHEST Annual Meeting 2018 in San Antonio and a discussion highlighting the latest updates made the CHEST Lung Cancer Screening Guidelines will take place

New Therapies For Type 1 diabetes

Researchers have identified a key target of the immune response that causes type 1 diabetes. Type 1 diabetes is an incurable autoimmune disease caused by the destruction of insulin-producing beta cells in the pancreas by immune cells called T cells.

This study, published in the journal PNAS (Proceedings of the National Academies of Sciences).

A specific type of T cell, a CD4+ T cell, recognizes a part of the beta cell (called an antigen) as foreign, initiating the immune response. Researchers have long been searching for the identity of the antigen that drives the disease.

Earlier work from A/Prof Mannering’s group showed that CD4+ T cells in the pancreas of an organ donor who had type 1 diabetes responded to a specific part of insulin’s precursor, proinsulin, known as C-peptide.

New Proteins Targeting Small Molecules

First such advance makes possible creation of new beta-barrel proteins to precisely target small molecules. For the first time, scientists have created, entirely from scratch,  a protein capable of binding to a small target molecule. The study was published in the journal Nature.