It's called the 'kiss of death'. Triple-negative breast cancer has no targeted drug therapy and, as such, the only hope for these patients is chemotherapy. Triple-negative breast cancer is aggressive and deadly. Patients are currently treated by chemotherapy but there is no guarantee of success—and unfortunately, for those that chemotherapy does not work, the survival rate remains only 12 months.
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Nurse practitioners (NPs) are providing an increasing proportion of primary care, which is in short supply in many areas of the country. NPs deliver quality care in retail clinics, community health centers, primary care and specialty medical practices.
A team of researchers led by Dr. Pierre Close, WELBIO researcher at the ULiège GIGA Institute and Dr. Francesca Rapino has uncovered a new therapeutic opportunity in the treatment of malignant melanoma that acquired resistance to targeted therapies
Thyroid dysfunction during the first half of pregnancy is associated with an increased risk of gestational diabetes, adding weight to the argument for thyroid screening among pregnant women. Specifically, the longitudinal study suggests that a higher level of free triiodothyronine (fT3) may be involved in the pathophysiology of gestational diabetes, which might be because of de novo synthesis or increased conversion of free thyroxine (fT4) to T3.
The study was published online in the Journal of Clinical Endocrinology & Metabolism, They are the first ones to show that the fT3:fT4 ratio is significantly related to an elevated risk of gestational diabetes, that "this builds on previous work showing a relationship between the ratio and other markers of glucose metabolism."
A team of researchers has identified the mode of action of viperin, a naturally occurring enzyme in humans and other mammals that is known to have antiviral effects on viruses such as West Nile, hepatitis C, rabies, and HIV. This discovery could allow researchers to develop a drug that could act as a broad-spectrum therapy for a range of viruses, including Zika.
The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate that pregnancies in women with rheumatoid arthritis are associated with premature delivery and low birth weight
The circadian rhythm has gotten more notice recently, scientists who discovered this day-night cycle. But popular knowledge focuses on how the circadian rhythm affects how we sleep, ignoring many of the other ways this cycle runs our lives. They cannot fall asleep and wake up at the same time, nor sleep and do heavy-duty digesting. The body needs time to rest and repair, and so it works on a set clock called the circadian rhythm.
Eighty-five percent of a sample of college students report engaging in risky sexual behavior and the knowledge of the risk of sexually transmitted infections (STI) seemed to have little to no effect on the behavior, according to a study by Ohio University's Reproductive and Sexual Health Initiative (RSHI).
Eating foods high in salt have been known to contribute to the high blood pressure, but does that linear relationship extend to increased risk of cardiovascular disease and death?
A study determines the effectiveness of warming anesthesia on the control of the pain produced during the administration of dental anesthesia injection and to analyze the role of Transient Receptor Potential Vanilloid-1 nociceptor channels in this effect.