All news from Anaesthesiology

Computational Geeks Uncovered a Therapy for Cancer

It's called the 'kiss of death'. Triple-negative breast cancer has no targeted drug therapy and, as such, the only hope for these patients is chemotherapy. Triple-negative breast cancer is aggressive and deadly. Patients are currently treated by chemotherapy but there is no guarantee of success—and unfortunately, for those that chemotherapy does not work, the survival rate remains only 12 months.

Thyroid Hormone Dysfunction Increased Risk Of Gestational Diabetes

Thyroid dysfunction during the first half of pregnancy is associated with an increased risk of gestational diabetes, adding weight to the argument for thyroid screening among pregnant women. Specifically, the longitudinal study suggests that a higher level of free triiodothyronine (fT3) may be involved in the pathophysiology of gestational diabetes, which might be because of de novo synthesis or increased conversion of free thyroxine (fT4) to T3.

The study was published online in the Journal of Clinical Endocrinology & Metabolism, They are the first ones to show that the fT3:fT4 ratio is significantly related to an elevated risk of gestational diabetes, that "this builds on previous work showing a relationship between the ratio and other markers of glucose metabolism."

Role of Viperin Against Virus Replication

A team of researchers has identified the mode of action of viperin, a naturally occurring enzyme in humans and other mammals that is known to have antiviral effects on viruses such as West Nile, hepatitis C, rabies, and HIV. This discovery could allow researchers to develop a drug that could act as a broad-spectrum therapy for a range of viruses, including Zika.

Body's Circadian Clocks Affecting The Sleep

The circadian rhythm has gotten more notice recently, scientists who discovered this day-night cycle. But popular knowledge focuses on how the circadian rhythm affects how we sleep, ignoring many of the other ways this cycle runs our lives. They cannot fall asleep and wake up at the same time, nor sleep and do heavy-duty digesting. The body needs time to rest and repair, and so it works on a set clock called the circadian rhythm.