All news from Anaesthesiology

CryoEM Captures An Opioid Drug Triggering The BIochemical Signaling

Scientists have used ultra-high-resolution cryo–electron microscopy (cryoEM) to capture the most detailed portrait ever of an opioid drug triggering the biochemical signaling cascade that gives it its power both for good and for ill.  Opioid drugs like morphine and fentanyl are a mainstay of modern pain medicine. The study was published in Nature.

But they also cause constipation, are highly addictive, and can lead to fatal respiratory failure if taken at too high a dose. Scientists have long sought to develop new opioid drugs that can drive away pain without these dangerous side effects, but holes in our understanding of exactly how opioids exert their various effects at a biological level has so far kept this dream at bay.

Research Offers Tips To Deal With Poison Ivy

In the present study, researchers discussed the first two months of summer coincide with the height of poison ivy seasonToxicodendron radicans, commonly known as eastern poison ivy or poison ivy, is a poisonous Asian and Eastern North American flowering plant that is well-known for causing urushiol-induced contact dermatitis

Universal Stroke Awareness Program Launched

In an effort to improve stroke recognition and reduce life-threatening pre-hospital delays worldwide, an international team lead by researchers at Penn Medicine created a universal stroke awareness program, Stroke 112. The team published encouraging results in Stroke about the program's acceptance in a non-English-speaking environment.

DNA Profiling Informative Way to Monitor UTI

Using shotgun DNA sequencing, Cornell University researchers have demonstrated a new method for monitoring urinary tract infections (UTIs) that surpasses traditional methods in providing valuable information about the dynamics of the infection as well as the patient's biological response

HIV and Diabetes: High Rates Increased the Risk of TB for South Africans

Since the 1980s, HIV has contributed to an increase in tuberculosis (TB) cases across the globe. Recently, diabetes has been found to be an important risk factor for TB. In a new study, Yale researchers investigated whether having both HIV and diabetes increases the risk of developing TB among individuals living in rural South Africa. The study, led by Sheela Shenoi and Pranay Sinha, is published in the International Journal of Tuberculosis and Lung Disease.