It's been known for years that humans and other mammals possess an antiviral gene called RSAD2 that prevents a remarkable range of viruses from multiplying. Now, researchers have discovered the secret to the gene's success: The enzyme it codes for generates a compound that stops viruses from replicating. The newly discovered compound, described in the online edition of Nature, offers a novel approach for attacking many disease-causing viruses.
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Deaths of children under 5 have dropped by nearly 20% in just two years in a poor, rural district in Madagascar—despite the island nation having the lowest health-spending level in the world
Understanding how and why the human body declines with age and how to slow or prevent it is an extremely important area of research, especially as the older population continues to grow. In addition to providing significant public health benefits, preventing age-related disease could have significant economic impacts on society.
However, aging is difficult to study, as it requires decades and decades of follow-up research. Microgravity offers a solution, as it can serve as a model for accelerated aging. Physiological changes occur approximately 10 times faster in microgravity and it contributes to loss of muscle and bone mass, cardiovascular degeneration, immune deficiency, and optic nerve swelling.
Even with a highly skilled neurosurgeon, the most effective anesthesia, and all the other advances of modern medicine, most of us would cringe at the thought of undergoing cranial surgery today. The study was published in World Neurosurgery.
A trepanation the act of scraping, cutting, or drilling an opening into the cranium was practiced around the world, primarily to treat head trauma, but possibly to quell headaches, seizures, and mental illnesses, or even to expel perceived demons.
Miscarriage and stillbirth are devastating events, and today, around 25% of these perinatal deaths are unexplained despite autopsy. Discovering the cause of such a loss is of great importance for the bereaved parents, both in providing an explanation and in helping them to understand the likelihood of a recurrence in future pregnancies
Influenza A (flu A) hijacks host proteins for viral RNA splicing and blocking these interactions caused replication of the virus to slow, according to new research published in Nature Communications by Kristin W. Lynch. Their results also suggest that infection with flu A may reduce splicing of some host genes, which could point to novel strategies for antiviral therapies.
Psychologists have discovered our brains use the same algorithm and neural architecture to evaluate the opportunity to gain information, as it does to evaluate rewards like food or money. They have a 'thirst for knowledge' but sometimes' ignorance is bliss', so they choose between this two mindstates at any given time. The study was published in the Proceedings of the National Academy of Sciences, also finds that people will spend money to both obtain advance knowledge of a good upcoming event and to remain ignorant of an upcoming bad event.
In the first 90 days of concurrent opioid and benzodiazepine use, the risk of opioid-related overdose increases five-fold compared to opioid-only use among Medicare recipients, according to a new study from the University of Pittsburgh School of Pharmacy, published today in JAMA Network Open
Protein fragments, called amyloid fibrils, in human semen significantly increase Ebola virus infection and protect the virus against harsh environmental conditions such as heat and dehydration. Researchers from the Perelman School of Medicine at the University of Pennsylvania report these findings in a study published this week in the Proceedings of the National Academy of Sciences (PNAS).
Vertical level mergers, which incorporate not just health care providers, but also insurers, retailers, and pharmacy benefit managers (PBMs), could pose challenges in primary care, according to an article published in Medical Economics.
Low-intensity shock wave treatment is effective for short-term treatment of erectile dysfunction, but its efficacy declines after two years, particularly in those with initial severe dysfunction, according to a study published in the July issue of The Journal of Urology