Sedation, together with analgesia, amnesia and muscle paralysis, is the end result of general anesthesia, which is an induced, reversible and controlled loss of consciousness. Sedation, on its own, is the depression of awareness, whereby a patient response to external stimuli becomes limited. Sedation may be minimal, moderate or deep.
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A single team of researchers from around the globe conducting two different studies has found more genes related to human intelligence and more that are associated with neuroticism. They have published separate papers outlining their work and findings in the journal Nature Genetics
Psychiatric disorders such as schizophrenia and bipolar disorder often run in families. In a new international collaboration, researchers explored the genetic connections between these and other disorders of the brain at a scale that far eclipses previous work on the subject. The team determined that psychiatric disorders share many genetic variants, while neurological disorders appear more distinct.
A new study showed that researchers developing nanoparticles that can zap tumors with significant amounts of heat under a low magnetic field. That's the promise of heated magnetic nanoparticles, a futuristic-sounding technology that could one day be used to fry and eradicate cancer cells without harming healthy tissue elsewhere in the body. The study was published online in the journal Small.
The nonprofit advocacy group Public Citizen has asked the US Food and Drug Administration (FDA) to immediately pull the gout drug febuxostat (Uloric, Takeda Pharmaceuticals) from the market following results of a large postmarketing study that showed higher rates of fatal cardiovascular (CV) events and all-cause mortality in patients taking the drug
A new study has brought science one step closer to a molecular-level understanding of how patterns form in living tissue. The researchers engineered bacteria that, when incubated and grown, exhibited stochastic Turing patterns: a 'lawn' of synthesized bacteria in a petri dish fluoresced an irregular pattern of red polka dots on a field of green.
A study shows that the stretchiness that allows living tissues to expand, contract, stretch, and bend throughout a lifetime is the result of a protein molecule called tropoelastin. Remarkably, this molecule can be stretched to eight times its length and always returns back to its original size.
Researchers have decoded the molecular structure of this complex molecule, as well as the details of what can go wrong with its structure in various genetically driven diseases. Tropoelastin is the precursor molecule of elastin, which along with structures called microfibrils is the key to the flexibility of tissues including skin, lungs, and blood vessels.
Researchers in Sweden have shown how data-driven AI could contribute to a better understanding of how prostate cancer develops, and even improve clinical diagnosis and treatment of the disease
The study was to determine whether poor sleep itself is a risk factor for AF. Poor sleep quality appears to be an important risk factor for atrial fibrillation, report scientists in the first study of its kind to demonstrate a relationship between poor sleep quality independent of sleep apnea and a higher risk of atrial fibrillation (AF). The study was published in HeartRhythm.
Chronic kidney disease (CKD) is a major global health problem. Unless intensive intervention is initiated, some patients can rapidly progress to end-stage kidney disease. However, it is often difficult to predict renal outcomes using conventional laboratory tests in individuals with CKD. Therefore, many researchers have been searching for novel biomarkers to predict the progression of CKD
Several states are likely dramatically underestimating the effect of opioid-related deaths because of incomplete death certificate reporting, with Pennsylvania leading the pack, according to a new analysis by the University of Pittsburgh Graduate School of Public Health.