For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth.
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Myanmar is yet to create a conducive environment for the safe and dignified return of Rohingyas forcibly displaced from its Rakhine State who took shelter in Bangladesh, a UN assessment indicates.
The first randomized study to compare general versus local anesthesia during transcatheter aortic valve replacement (TAVR) in patients with intermediate to high surgical risk found local anesthesia to be both safe and effective. In addition, the study found that a current generation balloon-expandable valve had similar outcomes to a current generation self-expanding one.
US hospitals continue to place cost and processing obstacles in the way of patients requesting their personal medical records, according to a study published online October 5 in JAMA Network Open.
Two new studies have found that regular long-term aspirin use may lower the risk of certain cancers, adding to the growing evidence that aspirin may play a role as a chemopreventive agent
Elite sport demands of athletes that they give the utmost of both body and mind. That physical rest is needed after training and competing is generally accepted, but relatively little consideration is given to mental recovery, knows researcher Yannick Balk. He proved that elite athletes—and their coaches—perform better if they relax regularly, and researched how they can best do that.
An international research team led by a scientist at the University of California, Riverside, has for the first time identified individual types of the human papillomavirus, or HPV, that are specifically linked to HIV infection.
Low-dose CT scan is more effective for the evaluation of new bone formation in progressive spondyloarthritis than x-ray, new data show. "You can see much more bone formation over a shorter period of time than with conventional radiography," said Désirée van der Heijde, MD, from the Leiden University Medical Center in the Netherlands, here at the International Congress on Spondyloarthritides 2018
Scientists using a powerful new technology that sequences RNA in 20,000 individual cell nuclei have uncovered new insights into biological events in heart disease. In animal studies, the researchers identified a broad variety of cell types in both healthy and diseased hearts and investigated in rich detail the "transcriptional landscape," in which DNA transfers genetic information into RNA and proteins.
This is the first time to our knowledge that massively parallel single-nucleus RNA sequencing has been applied to postnatal mouse hearts, and it provides a wealth of detail about biological events in both normal heart development and heart disease. The study was published in Genes & Development.
Researchers at The University of Texas Medical Branch at Galveston have developed less expensive way to produce vaccines that cuts the costs of vaccine production and storage by up to 80% without decreasing safety or effectiveness. The findings are currently available in EBioMedicine.