All news from Anaesthesiology

New ALS Therapy: Clinical Trials In Progress

New research indicates an investigational therapy for an inherited form of ALS extends survival and reverses signs of neuromuscular damage in mice and rats. The findings have led to a phase one/two clinical trial to investigate whether the drug could benefit people with ALS whose disease is caused by mutations in a gene called SOD1.

Structure And Functions Of Cornea And Ocular Surface

Important functions of the cornea in the eye include protecting the structures inside the eye, contributing to the refractive power of the eye, and focusing light rays on the retina with minimum scatter and optical degradation. Considerable advances have taken place in understanding the organization of collagen in the corneal stroma and its clinical significance. In this review, the structure and function of various components of the cornea and ocular surface are presented.

Soccer Might Cause Dangerous Injuries

With the final World Cup showdown, frenzied fans have seen the best soccer has to offer. While chasing down a ball during a game a player knocked heads with a rival so violently he awoke hours later in a hospital with a concussion – and no memory of the match he just played. But it's not just elite players who are susceptible to dangerous injuries from soccer, which has come under scrutiny in recent years for concussion management.

Exposure Of Spaceradiation Health Risk For Astronauts

Researchers examined the space radiation environment and the risk it poses to long-duration astronauts remains limited. There is a disparity between research results and observed empirical effects seen in human astronaut crews, likely due to the numerous factors that limit terrestrial simulation of the complex space environment and extrapolation of human clinical consequences from varied animal models.

Given the intended future of human spaceflight, with efforts now to rapidly expand capabilities for human missions to the moon and Mars, there is a pressing need to improve upon the understanding of the space radiation risk, predict likely clinical outcomes of interplanetary radiation exposure, and develop appropriate and effective mitigation strategies for future missions.