The Network for Excellence in Neuroscience Clinical Trials, or NeuroNEXT, a research program that helps streamline Phase II clinical trials for brain disorders, has been renewed for five more years, with several new centers joining the program. NeuroNEXT is supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health.
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Scientists have used the atomic resolution structural models of proteins from X-ray crystallography, nuclear magnetic resonance spectroscopy, and more recently cryo-electron microscopy. However, not all proteins relent to structural analyses using these approaches, and as the depth of knowledge increases, additional data elucidating a mechanistic understanding of protein function is desired.
Four cardiology societies issued a joint statement for requirements for centers with existing or new transcatheter aortic valve replacement (TAVR) programs, which updates a 2012 statement.
Researchers have identified a protein complex that might explain why some cancer patients treated with the revolutionary new anti-cancer drugs known as PARP inhibitors develop resistance to their medication. They showed that Shieldin so called because it shields the ends of broken DNA regulates DNA repair and could be a useful marker for identifying which patients are likely to respond poorly to PARP inhibitors. The study was published in Nature Cell Biology.
A naturally occurring hormone could help make chemotherapy much more effective for many Australians with lung cancer, according to new findings from Sydney and Melbourne researchers. And the hormone—known as follistatin—also appears to prevent kidney damage, a serious side effect of chemotherapy.
Researchers describe the microscopic anatomy of the posterior cruciate ligament femoral insertion in order to identify and establish differences between the direct and indirect insertions of this ligament.
According to the new study, scientists have shown that genetic variation may increase the risk of severe liver damage in Caucasians with chronic hepatitis B infection
The government is planning to introduce a state policy for hospital infection prevention and control. The move assumes significance given the fact that during the recent Nipah outbreak several people who succumbed to the disease were infected with the deadly virus during their hospital stay.
According to a study, researchers examined that older, overweight scuba divers are being urged to shed pounds to avoid an underwater heart attack. The study was published in the European Journal of Preventive Cardiology, a publication of the European Society of Cardiology (ESC).
Long-term use of either cannabis or cannabis-based drugs impairs memory say, researchers. The study has implications for both recreational users and people who use the drug to combat epilepsy, multiple sclerosis, and chronic pain