Thousands of experts and activists descend on Amsterdam to bolster the battle against AIDS amid warnings that "dangerous complacency" may cause a resurgence of the epidemic that has already killed 35 million people.
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A long-studied factor controlling human sleep cycles actually has two forms, one that keeps a key protein stable and another that promotes its degradation. From the heart and lungs that propel our blood to our rumbling stomachs at lunchtime and a feeling of tiredness in the evening, our bodies keep steady rhythms day in and day out.
This 'circadian clock' is a series of tightly controlled cycles of specific amounts of proteins that make us either sleepy or wakeful. It has recently attracted public attention with the 2017 Nobel Prize for Physiology or Medicine, but numerous aspects of the clock's functions or how it regulates our health remain a mystery.
Diagnosed with type 2 diabetes, high cholesterol, and borderline high blood pressure, Dana Hayes pursued bariatric surgery in hopes of living a healthier life. "I struggled with weight my whole life, but this was a place I'd never been before," she said.
Multiple pregnancies might make women's cells age more quickly, researchers suggested according to the research from the Northwestern University
In one of the largest studies of its kind, researchers analyzed chikungunya and dengue outbreak data from 76 countries over a period of 50 years, focusing on regions across the Indian Ocean that are hard hit by these and other mosquito-borne infectious diseases.
In Asian patients, symptomatic venous thromboembolism (VTE) after gastrectomy is extremely rare, and pharmacological prophylactic measures may prompt bleeding complications, Korean researchers said.
Experimental stem cell therapies for eye conditions are being offered at dozens of unregulated clinics in the United States, and some of these procedures are harmful, researchers report
For patients diagnosed with a Staphylococcus aureus infection, often referred to as a staph or MRSA infection, every minute counts. The bacteria create havoc in the body. The immune system goes into overdrive. The heightened immune response can lead to sepsis, which kills 30 to 50% of the people who develop it. In Canada, sepsis is the 12th leading cause of death.
Pierre Fabre today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion recommending approval of BRAFTOVI® (encorafenib) and MEKTOVI® (binimetinib) in combination for the treatment of adult patients with unresectable or metastatic melanoma with a BRAFV600 mutation.
The CHMP recommendation will now be reviewed by the European Commission (EC), which has the authority to approve medicines for the European Union (EU). "We are delighted to be one step closer to bringing BRAFTOVI and MEKTOVI to patients with advanced BRAF-mutant melanoma in Europe. If the European Commission approves BRAFTOVI and MEKTOVI, this will be a new treatment option for these patients who currently have a challenging prognosis.
"The MERIT-UC trial showed that MTX was not superior to placebo in maintaining a steroid-free response or remission among patients who achieved steroid-free response during induction therapy," co-author Dr. Edward L. Barnes of the University of North Carolina.
Children and young people with attention deficit hyperactivity disorder (ADHD) are at an increased risk of injury, a study at the University of Nottingham has found