All news from Anaesthesiology

How To Adjust Our Circadian Rhythms And Get Sleep ?

Researchers determine that light exposure and mealtime may be the key to resetting the "master clock” in the brain. In casual conversation, the “biological clock” is often referred to when starting a family but officially, our biological clocks, or our circadian rhythms, are how our bodies know when to go to sleep at night and when to wake up in the morning.

With a few notable exceptions, most of us live lives in which we work at day and sleep at night, loosely following the rise and setting of the sun. However, as any insomniac can tell you, it’s also super easy for our circadian rhythms to go off-kilter.

Scanning Electron Microscopy Used In Biomedical Research

Researchers find solutions to the issues that are faced daily in medicine by combining biology with mathematics, physics, or chemistry. These research fields address various problems through the development of bionic parts, implants, medical devices and imaging equipment, along with tissue engineering. It involves extremely delicate and very detailed work that requires very high precision.

Scanning electron microscopy (SEM) imaging is a robust tool to study such details at the nanoscale and to push the analyzes further. SEMs are highly versatile instruments that are shown to be particularly useful in various biomedical research fields, ranging from orthodontics to bone grafts and tissue engineering.

Enzyme Use Aminoacid For Catalysis

Researchers have created a new enzyme with an unnatural amino acid as its active center. They made the enzyme by modifying an antibiotic binding protein which normally acts as a bacterial transcription factor. Further modifications of the reactive site can create different enzymes for use in chemical synthesis. The study of the new enzyme was published in Nature Chemistry.

Medical Errors In The Emergency Department

Medical errors are estimated to cause 250,000 deaths per year in the US. Previously, research on admitted patients suggested that errors are due to the way doctors process the data they have about patients, in other words, doctors have the right information, but might not act on it in the best way.

The emergency department(ED) is a very different clinical environment from the inpatient wards, with frequent interruptions and often incomplete or unreliable information. The new study published in the Journal Diagnosis 

It shows that doctors in an emergency department with trainees make similar types of errors to those made in admitted patients – more information processing errors are made than errors of inadequate knowledge or inadequate information.

Gene Controls Tissue In Bone Marrow

In an unexpected discovery, UCLA researchers have found that a gene is previously known to control human metabolism also controls the equilibrium of bone and fat in bone marrow as well as how an adult stem cell expresses its final cell type.

The findings could lead to a better understanding of the disruption of the bone-to-fat ratio in bone marrow as well as its health consequences and also point to the gene as a promising therapeutic target in the treatment of osteoporosis and skeletal aging. The study was published online in the journal Cell Stem Cell.

PEACHI project: Vaccine Strategies Targeting HIV and HCV

An estimated 2.3 million people globally are infected with both human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). The EU-funded PEACHI project aimed to develop simple, affordable and effective vaccine strategies targeting both viruses, which can be given individually or in combination. In particular, this could increase the life expectancy of co-infected people receiving antiretroviral therapy for HIV-1, for whom HCV is a leading cause of death.