All news from Anaesthesiology

A Single-Cell Atlas of the Lung Cell

In separate studies published online in Nature, two independent research teams report the discovery of a new, rare type of cell in the human airway. These cells appear to be the primary source of activity of the CFTR gene, mutations to which cause cystic fibrosis, a multiorgan disease that affects more than 70,000 people worldwide.

Transmission Electron Microscopy Limitations

A study determines the limitations of Transmission electron microscopy (TEM) has found its way into cell biology since 1940. When compared with light microscopes, TEM can achieve a very high resolution due to the shorter wavelength of the electron beam it uses. This feature enables TEM to visualize the structure of the cells such as membrane systems, cilia, organelles and its complexity. Regardless of the advantages, TEM has its own limitations.

Comparative Analysis Of Single-Cell RNA Sequencing Methods

A team has improved both the sensitivity and efficiency of a popular method for single-cell RNA sequencing, which yields a molecular fingerprint for individual cells based on their patterns of gene activity. The human body is made up of on the order of 13 billion cells and each of them has a distinct molecular profile.

Even cells in the same tissue can differ, often subtly, from one another, and their activities can vary over time. This is why single-cell analyses provide such a powerful tool for the characterization of cellular heterogeneities and the complex mechanisms that account for them. Single-cell technologies are already revolutionizing biology. The study was published in Nature Communications.

Anatomy Of Human Butt

A study evaluates the evolutionary history and present-day biology of the human asscheek. It’s a story that starts 350 million years ago, with massive primordial tails, and winding its way through the millennia ends on those time-whittled marvels of ergonomic flesh-and-muscle you’re probably sitting on right now.

The answer is both, probably. But while whole careers have been spent tracing the origins of human self-awareness, the lowly butt cheek has to this point not warranted even a short monograph. These fleshy, sometimes hairy, alternately hilarious, erotic and mundanely functional appendages.

Most Older Adults Hang On Leftover Opioids

Nearly a third of older Americans filled a prescription for an opioid during the past 2 years, and many of them did not receive sufficient counseling on the risks of taking opioids, how to reduce their use, when to switch to a nonopioid pain reliever, or what to do with leftover pills, according to a new poll.