High-volume referral centers throughout the United States are seeing a consistent decrease in low-grade prostate cancer and an absolute increase in intermediate- and high-risk disease compared with earlier years before the 2012 US Preventive Services Task Force (USPSTF) recommended against prostate-specific antigen (PSA)–based screening
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In separate studies published online in Nature, two independent research teams report the discovery of a new, rare type of cell in the human airway. These cells appear to be the primary source of activity of the CFTR gene, mutations to which cause cystic fibrosis, a multiorgan disease that affects more than 70,000 people worldwide.
A study determines the limitations of Transmission electron microscopy (TEM) has found its way into cell biology since 1940. When compared with light microscopes, TEM can achieve a very high resolution due to the shorter wavelength of the electron beam it uses. This feature enables TEM to visualize the structure of the cells such as membrane systems, cilia, organelles and its complexity. Regardless of the advantages, TEM has its own limitations.
Despite constituting half of United States medical school graduates, women continue to be underrepresented in the field of surgery, accounting for only one-third of general surgery residency applicants.
A team has improved both the sensitivity and efficiency of a popular method for single-cell RNA sequencing, which yields a molecular fingerprint for individual cells based on their patterns of gene activity. The human body is made up of on the order of 13 billion cells and each of them has a distinct molecular profile.
Even cells in the same tissue can differ, often subtly, from one another, and their activities can vary over time. This is why single-cell analyses provide such a powerful tool for the characterization of cellular heterogeneities and the complex mechanisms that account for them. Single-cell technologies are already revolutionizing biology. The study was published in Nature Communications.
A study evaluates the evolutionary history and present-day biology of the human asscheek. It’s a story that starts 350 million years ago, with massive primordial tails, and winding its way through the millennia ends on those time-whittled marvels of ergonomic flesh-and-muscle you’re probably sitting on right now.
The answer is both, probably. But while whole careers have been spent tracing the origins of human self-awareness, the lowly butt cheek has to this point not warranted even a short monograph. These fleshy, sometimes hairy, alternately hilarious, erotic and mundanely functional appendages.
In patients with chronic kidney disease, medical nutrition therapy can slow the progression and significantly reduce healthcare costs. But 90% of non-dialysis kidney disease patients never meet with a dietitian, according to a report in the Journal of the Academy of Nutrition and Dietetics
The textbook approach to managing disease outbreaks focuses on three factors—pathogen, host, and environment—but it leaves out one critical component in the case of afflictions such as Zika, malaria, and Lyme: the insect or arthropod responsible for transmission to humans.
Nearly a third of older Americans filled a prescription for an opioid during the past 2 years, and many of them did not receive sufficient counseling on the risks of taking opioids, how to reduce their use, when to switch to a nonopioid pain reliever, or what to do with leftover pills, according to a new poll.
Johns Hopkins Medicine scientists say they have found new evidence in lab-grown mouse brain cells, called astrocytes, that one root of Alzheimer's disease may be a simple imbalance in acid-alkaline—or pH—chemistry inside endosomes, the nutrient and chemical cargo shuttles in cells
Men seek and start treatment for HIV/AIDS when they are much sicker compared to women, according to a study by researchers from around the world, including at the University of Toronto's Dalla Lana School of Public Health.
While blood and marrow transplants can save the life of a pediatric cancer patient, research out of the University of Alabama at Birmingham found that those patients may be at an increased risk of premature death even years or decades after the procedure as compared with the general population.