All news from Anaesthesiology

New Brain Cells In Adults Grow Old As They Age

Scientists find signs of new brain cells in adults as old as 79. They present new evidence that our brains continue to make hundreds of new neurons a day, even after we reach our 70s, in a process known as neurogenesis. To come to this conclusion, they looked at the brains of 28 deceased people aged 14 to 79. Their goal was to see whether aging affects neuron production. The study was published in Cell Stem Cell.

Intestinal Virus Changes With Inflammatory Bowel Disease, Study

Unexpected patterns emerged in the microbial and viral communities of mice with intestinal inflammation during a study that examined the intestinal tracts of diseased and healthy mice. Spearheaded by researchers at North Carolina State University, the University of Texas Southwestern Medical Center and the University of Colorado, the study could lead to better understanding of potential causes and markers of inflammatory bowel disease.

New Class Of Drugs May Lower Heart Disease Risk By Targeting Gut Microbes

Researchers have designed a potential new class of drugs that may reduce cardiovascular risk by targeting a specific microbial pathway in the gut. Unlike antibiotics, which non-specifically kill gut bacteria and can lead to adverse side effects and resistance, the new class of compounds prevents microbes from making a harmful molecule linked to heart disease without killing the microbes, which are part of the gut flora and may be beneficial to overall health. The study was published in Nature Medicine.

Patients Receive Postoperative Opioid Prescription After Ambulatory Surgery

Each year in the United States, more than 100 million people undergo surgical procedures, including 53 million performed in the ambulatory setting. Findings suggest that nearly all of these patients will receive a postoperative opioid prescription, and 1 study found continued use in 7.7% of opioid-naive patients 1 year after surgery.

Other results have linked the prescription of opioids after short-stay surgery to a 44% greater risk for prolonged opioid use. While judicious management of opioids is warranted in all patients, the current growing opioid epidemic warrants meticulous weaning of pain medications postoperatively.

The study was published in Current Pain and Headache Reports. In the ambulatory surgery settings, such direction is very necessary given limited immediate postoperative follow-up for patients being discharged from the hospital.

Pathways in which Ebola virus Could Enter Cells Uncovered

A new study at Texas Biomedical Research Institute is shedding light on the role of specific proteins that trigger a mechanism allowing Ebola virus to enter cells to establish replication. The work, published in a supplement to The Journal of Infectious Diseases, was led by Staff Scientist Olena Shtanko. The BSL4 is a high-containment facility that houses research on diseases for which there are no approved vaccines or cures.