All news from Anaesthesiology

New Study Transforming Tissue Cells Into Skin Cells

Researchers have transformed tissue cells into skin cells to help heal serious wounds, a technique that could revolutionise care for victims of burns and other severe injuries.

The research is the culmination of a decade of work and holds promise for a variety of patients, including those with serious burns or elderly patients with bedsores and other recurring lesions. The study was published in the journal Nature, involves a technology called “cell reprogramming” in which genes are inserted into cells to change them from one form to another.

End-of-Life Decision To Seek Advance Care

Former first lady Barbara Bush died on April 17 at the age of 92 in her home in Houston, Texas after making the decision to seek advanced care directive home care hospice, or comfort care, for her terminal illness.

The respected and beloved first lady was suffering from congestive heart failure and chronic obstructive pulmonary disease, and had decided a couple of days prior to her passing that she would “not seek additional medical treatment and will focus on comfort care.

'Jumpstart' Rhythmic Breathing at Birth, Mechanism Elaborated

The common expression, 'As easy as breathing,' is truly misleading. Breathing, as it is performed by higher vertebrates, is a complex biological function involving many types of neurons. It requires chemosensory neurons to sense oxygen and carbon dioxide levels in the blood and motor neurons to control muscle movement.

It also needs specialized neurons to establish correct breathing rhythms at birth and subsequently maintain it throughout life. The mechanism by which actions of these diverse groups of neurons are finely orchestrated to produce precise breathing rhythms has remained a mystery. The study is published in the journal eLife.

No Accuracy from Mouse Models in Mimicking Severity of Gonorrhea Infection, Findings

There is an urgent need to develop a vaccine to prevent gonorrhea infection due to rapidly increasing incidence and growing antibiotic resistance.

BUSM researchers have been investigating the use of animal models of gonorrhea, to study how the infection evolves and for potential use to determine the efficacy of next-generation vaccines. They found that the mouse model may not fully reflect the severity of the infection and the types of immune responses seen in humans.